DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cd and mpo

DIOPT Version :9

Sequence 1:	NP_651081.1	Gene:	cd / 42681	FlyBaseID:	FBgn0263986	Length:	830	Species:	Drosophila melanogaster
Sequence 2:	XP_002935236.4	Gene:	mpo / 100490938	XenbaseID:	XB-GENE-482502	Length:	725	Species:	Xenopus tropicalis

Alignment Length:	611	Identity:	203/611 - (33%)
Similarity:	306/611 - (50%)	Gaps:	61/611 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   215 NARYRRSTGVCNNKQHPRTYGASMVPYRRMVSPDYADGIAAPRVSHHGR------LPPARQVS-- 271
            |:|||..||.|||::.| .:|.|..||.|::...|.|..:.||.....|      ||.||.||
Frog   143 NSRYRTFTGECNNRRFP-NFGVSNRPYTRLLPAQYEDSRSLPRGWTENRRINGFMLPLARAVSNQ 206

  Fly   272 -LKIHRSSYETDSNFTVMLAVFGQFMDHDITATSLTTSQEG--ESIDCCVAATREQHPECYPVDI 333
             |:........|:..::|...:||::|||:.....|.::..  :.|||..:..:|.  .|:|:.|
Frog   207 ILQFPEREQTLDNQRSLMFMQWGQWIDHDVDLAPETPARSSFLKGIDCDHSCAKEL--PCFPLRI 269

  Fly   334 LPDDPYYKQYNISCMNFVRSAPA--PTGRFGPRM-QLNQATAFIDASVVYGNLEQRQNQLRSFIN 395
            .|:||.. |....|:...||:||  |    ||.: |:|..|:::|||.|||:.......||:...
Frog   270 PPNDPRI-QNRSDCIPLFRSSPACVP----GPVLEQINVLTSYVDASQVYGSTNDLARMLRNNTA 329

  Fly   396 GSLRMFV-----TDDGRQLLPISSNPADGCNRVQMTRLGKYCFESGDDRANENLLLTSMHLLWAR 455
            |.|.:..     ||.|...||.|:...|.|.....|. |..||.:||.|.:|...||:.|.::.|
Frog   330 GQLGLMAVNTRFTDGGLPYLPFSTMKEDFCVLTNETS-GLPCFLAGDARVSEQPGLTAFHTIFVR 393

  Fly   456 HHNYLARQLQEQNPHWEDERLYQEARKILGAQMAHITYNEFLPVLLGKNISEAKGLLPAKHNLNA 520
            .||.:||:|:..||:|..|.::||||||:||....|.|.::||:|||.::..   :||..
Frog   394 EHNRIARELRRINPNWTGEIIFQEARKIVGAVEQKINYKDYLPLLLGSSMPR---VLPRY----- 450

  Fly   521 PDTYDPEVDPSIANCFAAAAFRFAHTLL-PGLFNI---SRDNSTPEAIELHKMLFNPFSLWAEHG 581
             .||:..|:|..:|.| :..||..||:: |.:|.:   .|.:|:...:.||...||.:.:..|.|
Frog   451 -TTYNDSVNPGASNVF-SLVFRMGHTMIQPFIFRLVDGYRASSSLPPVPLHLTFFNTWRVILEGG 513

  Fly   582 IDHAL--MTAANTPVMQVDRFFSLEVTQKLFEGTAEDRVPLCGLDLVSLNIQRGRDHGIPSYPVF 644
            :|..|  :.|....:....:....::|..|||     .....||||.::|:|||||||:|.|..|
Frog   514 VDPLLRGLIANKAKLNTQTQILVTQLTDHLFE-----LFKRLGLDLGAINMQRGRDHGLPGYNAF 573

  Fly   645 RRHCRLPTVDTWEEMSQAIDNATL-DSIRQIYESPQDVDVYTGALSEPPLDGAIFGPLLSCMVSD 708
            ||.|.|.......|::..:.|..| ..:..:|.:|.::|::.||::||.:.....|.||:|::.|
Frog   574 RRLCGLSQPRNESELAAVLRNNQLAQKLISLYGTPDNIDIWMGAVAEPLITNGRVGELLACLIGD 638

  Fly   709 QFLRLKLGDSHWYERKMGPQKFTKAQLAEIYKTSLAAIICRNSDGITRVREHVMQRLRDGGNP-- 771
            ||.|.:.||..:|||   ...||.|||..|.:.|||.|:|.|    ||:.|......:....|
Frog   639 QFRRTRDGDRFYYER---ASVFTPAQLRSIERASLARIVCDN----TRITEVPRDVFKANNYPAN 696

  Fly   772 HVDCQDLEGFHFNFEPWSEKQQPQDL 797
            .|.|..:..  .:..||..::..::|
Frog   697 FVRCSSIPA--LDLSPWRRRRGGEEL 720

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cd	NP_651081.1	An_peroxidase	218..755	CDD:281139	192/562 (34%)
cd	NP_651081.1	peroxinectin_like	364..750	CDD:188655	139/398 (35%)
mpo	XP_002935236.4	An_peroxidase	146..688	CDD:397287	195/572 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010