DRSC/TRiP Functional Genomics Resources

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Protein Alignment: Dph5 and DPH5

Sequence 1:NP_524452.4 Gene:Dph5 FlyBaseID:FBgn0024558 Length:281 Species:Drosophila melanogaster
Sequence 2:NP_001070862.1 Gene:DPH5 HGNCID:24270 Length:285 Species:Homo sapiens

Alignment Length:271 Identity:172/272 (63%)
Similarity:214/272 (79%) Gaps:0/272 (0%)


  Fly     1 MFYLIGLGLGDLKDITVKGLEIVKQCSRVYLEMYTSILGCSLEDMQEFYGRPLLLADRDLVEQGA 65
            |.|||||||||.|||||||||:|::|||||||.|||:|....|.::|||||.|::|||:.|||.|
Human     1 MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREEVEQEA 65

  Fly    66 DEILAGAGESDVALLVVGDPFGATTHTDFILRAKEKNIPYKVIHNASIMNAVGCCGLQLYKFGET 130
            |.||..|..||||.||||||||||||:|.:|||.:..|||:||||||||||||||||||||||||
Human    66 DNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCCGLQLYKFGET 130

  Fly   131 VSIPYWDETWKPDSFYDKIKLNRLHNMHTLCLLDIKVKEPTPESLMRKRKEYMPPRFMTVAEAAH 195
            |||.:|.:||:|:||:||:|.||.:.|||||||||||||.:.|:|::.||.|.|||:|:|.:||.
Human   131 VSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQ 195

  Fly   196 QLLSIVEKKDSLEKNTVLNEQSLCVGLARVGQESQQIAVGTLLEMRSTDLGGPLHSLIIPAKEMH 260
            |||.||:.:....:...:.|::|||||||||.:.|:||.|||.:|.:.|||.|||||||....:|
Human   196 QLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQMCTVDLGEPLHSLIITGGSIH 260

  Fly   261 PLEVEFLQQYA 271
            |:|:|.|..::
Human   261 PMEMEMLSLFS 271

Known Domains:


GeneSequenceDomainRegion External IDIdentity
Dph5NP_524452.4 PTZ00175 1..270 CDD:185500 172/269 (64%)
DPH5NP_001070862.1 PTZ00175 1..272 CDD:185500 172/272 (63%)
S-adenosyl-L-methionine binding. {ECO:0000250} 112..113 1/1 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 C174000752
eggNOG 1 0.900 E1_COG1798
Hieranoid 1 1.000
Homologene 1 1.000 H6471
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010
OrthoDB 1 1.010 D1018517at2759
OrthoFinder 1 1.000 FOG0003877
OrthoInspector 1 1.000 T1073216
orthoMCL 1 0.900 OOG5_127443
Panther 1 1.100 LDO PTHR10882
Phylome 1 0.910 0.667 Consistency score
RoundUp 1 1.030 avgDist Average_Evolutionary_Distance R340
TreeFam 1 0.960
User_Submission 00.000 Not matched by this tool.
1312.750

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