Protein Alignment CCT1 and CCT3

DIOPT Version :10

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_012520.1
• Gene: CCT3 / 853438
• SGDID: S000003551
• Length: 534
• Species: Saccharomyces cerevisiae
• Alignment Length: 540
• Identity: 164/540 - (30%)
• Similarity: 279/540 - (51%)
• Gaps: 45/540 - (8%)

  Fly    14 RQSGASVRTQNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLLEVEHPAAKVL 78
            |.:|...:..|:.||.::::::::.|||..:.|||:|.:|.:.:||||..|||.::|.|||||.:
Yeast    14 RTTGRQAQISNITAAKAVADVIRTCLGPKAMLKMLLDPMGGLVLTNDGHAILREIDVAHPAAKSM 78

  Fly    79 VELAQLQDEEVGDGTTSVVILAAELLKN-ADELVKQKIHPTSIISGYRIACKEACKYISEHLTAP 142
            :||::.||||||||||:|:|||.|:|.. |..|:::.|||..||...:.|..:|.:.|.: ::.|
Yeast    79 LELSRTQDEEVGDGTTTVIILAGEILAQCAPYLIEKNIHPVIIIQALKKALTDALEVIKQ-VSKP 142

  Fly   143 VDELGRDSLINIAKTSMSSKIIGADAEFFSAMVVDAAQSVKI---TDPRGQAAYSI---KAINVL 201
            ||.....::..:.:.|:.:|.:...:|....:.:||.::|:.   ....|:..:.|   :.:.|.
Yeast   143 VDVENDAAMKKLIQASIGTKYVIHWSEKMCELALDAVKTVRKDLGQTVEGEPNFEIDIKRYVRVE 207

  Fly   202 KAHGKSARESVLIPGYALNCTIASQQMPKKIVNAKIACLDFSLQKTKMKMGVQVLINDPDKLEAI 266
            |..|....:|.::.|..||..:...:|.:.|.|.::..||..|:..|.:....:.|...:....|
Yeast   208 KIPGGDVLDSRVLKGVLLNKDVVHPKMSRHIENPRVVLLDCPLEYKKGESQTNIEIEKEEDWNRI 272

  Fly   267 RARELDITKERINM----ILGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKATG 327
                |.|.:|::.:    ||.....:|:...||.||...|.::.|...:|||||||...||:.||
Yeast   273 ----LQIEEEQVQLMCEQILAVRPTLVITEKGVSDLAQHYLLKGGCSVLRRVKKSDNNRIARVTG 333

  Fly   328 AAFITSLTNMDGEES--------FDASMVGEAAEVAQERICDDELILIKGTKARAAASIILRGPN 384
            |..:..:.::  :||        |...|:|           |:....:...|...|.:|:|||.:
Yeast   334 ATIVNRVEDL--KESDVGTNCGLFKVEMIG-----------DEYFSFLDNCKEPKACTIMLRGGS 385

  Fly   385 DFYCDEMERSVHDALCVVKRVLESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLL 449
            ....:|::|::.||:.|.:.|:.|..:..|||..|.|:|:.|...|..|...:|......|.::.
Yeast   386 KDILNEIDRNLQDAMAVARNVMLSPSLSPGGGATEMAVSVKLAEKAKQLEGIQQWPYQAVADAME 450

  Fly   450 VIPKTLSVNAAKDATDLVAKLRSYHNSSQTKPERSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKI 514
            .||:||..||..|...|:::||:.|......        ||:|..:|.:.|....|:.||.:.|.
Yeast   451 CIPRTLIQNAGGDPIRLLSQLRAKHAQGNFT--------TGIDGDKGKIVDMVSYGIWEPEVIKQ 507

  Fly   515 KSLKFATEAAITILRIDDMI 534
            :|:|.|.|:|..:||:||::
Yeast   508 QSVKTAIESACLLLRVDDIV 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	164/540 (30%)
CCT3	NP_012520.1	chap_CCT_gamma	4..533	CDD:274085	164/540 (30%)