Protein Alignment CCT1 and TCP1

DIOPT Version :10

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_010498.1
• Gene: TCP1 / 851798
• SGDID: S000002620
• Length: 559
• Species: Saccharomyces cerevisiae
• Alignment Length: 538
• Identity: 341/538 - (63%)
• Similarity: 429/538 - (79%)
• Gaps: 6/538 - (1%)

  Fly     8 LSIAGTRQSGASVRTQNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLLEVEH 72
            |.:.|.:.||..:|.|||:|.::::|:||||||||||||||||||||.||||||||||.||:|:|
Yeast    13 LFLGGEKISGDDIRNQNVLATMAVANVVKSSLGPVGLDKMLVDDIGDFTVTNDGATILSLLDVQH 77

  Fly    73 PAAKVLVELAQLQDEEVGDGTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACKYISE 137
            ||.|:||||||.||.|:|||||||||:|:||||.|:||||.|||||:||:|:|:|.:||.::|:|
Yeast    78 PAGKILVELAQQQDREIGDGTTSVVIIASELLKRANELVKNKIHPTTIITGFRVALREAIRFINE 142

  Fly   138 HLTAPVDELGRDSLINIAKTSMSSKIIGADAEFFSAMVVDAAQSVKITDPRGQAAYSIKAINVLK 202
            .|:..||.||:::|||||||||||||||||::|||.|||||..:||..:.:|:..|.:||:||||
Yeast   143 VLSTSVDTLGKETLINIAKTSMSSKIIGADSDFFSNMVVDALLAVKTQNSKGEIKYPVKAVNVLK 207

  Fly   203 AHGKSARESVLIPGYALNCTIASQQMPKKIV--NAKIACLDFSLQKTKMKMGVQVLINDPDKLEA 265
            ||||||.||:|:||||||||:|||.|||:|.  |.||||||.:|||.:|.||||:.|:||::||.
Yeast   208 AHGKSATESLLVPGYALNCTVASQAMPKRIAGGNVKIACLDLNLQKARMAMGVQINIDDPEQLEQ 272

  Fly   266 IRARELDITKERINMILGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKATGAAF 330
            ||.||..|..||:..|:..|..|||.:.|:||||:|.||||..|.|||.||.||:.||:||||..
Yeast   273 IRKREAGIVLERVKKIIDAGAQVVLTTKGIDDLCLKEFVEAKIMGVRRCKKEDLRRIARATGATL 337

  Fly   331 ITSLTNMDGEESFDASMVGEAAEVAQERICDDELILIKGTKARAAASIILRGPNDFYCDEMERSV 395
            ::|::|::|||:|::|.:|...||.|.:..|||.||||||...:::||||||.||:..||||||:
Yeast   338 VSSMSNLEGEETFESSYLGLCDEVVQAKFSDDECILIKGTSKHSSSSIILRGANDYSLDEMERSL 402

  Fly   396 HDALCVVKRVLESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVIPKTLSVNAA 460
            ||:|.||||.|||..||.|||||||||:|||:||||::.|||||||||||.:||:|||||:||||
Yeast   403 HDSLSVVKRTLESGNVVPGGGCVEAALNIYLDNFATTVGSREQLAIAEFAAALLIIPKTLAVNAA 467

  Fly   461 KDATDLVAKLRSYHNSSQ-TKPE---RSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKIKSLKFAT 521
            ||:::|||||||||.:|| .|||   |...:..|||||.|.:.|...||||||.:||:||||.|.
Yeast   468 KDSSELVAKLRSYHAASQMAKPEDVKRRSYRNYGLDLIRGKIVDEIHAGVLEPTISKVKSLKSAL 532

  Fly   522 EAAITILRIDDMIKLNPE 539
            ||.:.|||||.||.::||
Yeast   533 EACVAILRIDTMITVDPE 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	338/531 (64%)
TCP1	NP_010498.1	TCP1_alpha	17..549	CDD:239451	338/531 (64%)