Protein Alignment CCT1 and CCT4

DIOPT Version :10

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_010138.1
• Gene: CCT4 / 851412
• SGDID: S000002302
• Length: 528
• Species: Saccharomyces cerevisiae
• Alignment Length: 535
• Identity: 165/535 - (30%)
• Similarity: 288/535 - (53%)
• Gaps: 39/535 - (7%)

  Fly    14 RQSGASVRTQNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLLEVEHPAAKVL 78
            ::....||..|::||.|:::.:::||||.|:|||:....|::.::|||.|||:.:.:.||.|::|
Yeast    14 KEKPQEVRKANIIAARSVADAIRTSLGPKGMDKMIKTSRGEIIISNDGHTILKQMAILHPVARML 78

  Fly    79 VELAQLQDEEVGDGTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACKYISE--HLTA 141
            ||::..||.|.||||||||||...||..|:.|:.:.||||.|...::.|.|.:...:.|  |..:
Yeast    79 VEVSAAQDSEAGDGTTSVVILTGALLGAAERLLNKGIHPTIIADSFQSAAKRSVDILLEMCHKVS 143

  Fly   142 PVDELGRDSLINIAKTSMSSKIIGADAEFFSAMVVDAAQSVKITDPRGQAAYSIKAINVLKAHGK 206
            ..|   |:.|:..|.||:||||:...:.|.:.:.||:.  :||:|...:.. .:..|.::|..|.
Yeast   144 LSD---REQLVRAASTSLSSKIVSQYSSFLAPLAVDSV--LKISDENSKNV-DLNDIRLVKKVGG 202

  Fly   207 SARESVLIPGYALNCT-IASQQMPKKIVNAKIACLDFSLQKTKMKMGVQVLINDPDKLEAI---- 266
            :..::.:|.|..|..| |.|...|.:...|||..:.|.:...|......:::||..:::.|
Yeast   203 TIDDTEMIDGVVLTQTAIKSAGGPTRKEKAKIGLIQFQISPPKPDTENNIIVNDYRQMDKILKEE 267

  Fly   267 RARELDITKE----RINMILGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKATG 327
            ||..|:|.|:    :.|::|   :...::...|:||.:.:..:...|.|:.:::.:::.::|..|
Yeast   268 RAYLLNICKKIKKAKCNVLL---IQKSILRDAVNDLALHFLSKLNIMVVKDIEREEIEFLSKGLG 329

  Fly   328 AAFITSLTNMDGEESFDASMVGEAAEVAQERICDDELIL----IKGTKARAAASIILRGPNDFYC 388
            ...|..:      |.|....:| :|::.:|...|...|:    |:...||...|:::||.|:...
Yeast   330 CKPIADI------ELFTEDRLG-SADLVEEIDSDGSKIVRVTGIRNNNARPTVSVVIRGANNMII 387

  Fly   389 DEMERSVHDALCVVKRVLESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVIPK 453
            ||.|||:||||||::.:::.:.::||||..|..:|..|...|.|:...:.....|||.:|.|||.
Yeast   388 DETERSLHDALCVIRCLVKERGLIAGGGAPEIEISRRLSKEARSMEGVQAFIWQEFASALEVIPT 452

  Fly   454 TLSVNAAKDATDLVAKLRSYHNSSQTKPERSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKIKSLK 518
            ||:.||..::..:|.:|||.|.:.    |.:|    |:.:......:..:..:|:|.:....::.
Yeast   453 TLAENAGLNSIKVVTELRSKHENG----ELND----GISVRRSGTTNTYEEHILQPVLVSTSAIT 509

  Fly   519 FATEAAITILRIDDM 533
            .|:|...:||||||:
Yeast   510 LASECVKSILRIDDI 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	165/535 (31%)
CCT4	NP_010138.1	chap_CCT_delta	11..528	CDD:274083	165/535 (31%)