Protein Alignment CCT1 and CCT3

DIOPT Version :10

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_005989.3
• Gene: CCT3 / 7203
• HGNCID: 1616
• Length: 545
• Species: Homo sapiens
• Alignment Length: 534
• Identity: 173/534 - (32%)
• Similarity: 288/534 - (53%)
• Gaps: 20/534 - (3%)

  Fly    14 RQSGASVRTQNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLLEVEHPAAKVL 78
            |:||..|::.|:.||.:|::|:::.|||..:.|||:|.:|.:.:||||..|||.::|:|||||.:
Human    16 RESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHPAAKSM 80

  Fly    79 VELAQLQDEEVGDGTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACKYISEHLTAPV 143
            :|:::.||||||||||||:|||.|:|..|:..::|::|||.:||.||.|..:....:.: ::.||
Human    81 IEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKK-ISIPV 144

  Fly   144 DELGRDSLINIAKTSMSSKIIGADAEFFSAMVVDAAQSVKITDPRGQAAYSIKA-INVLKAHGKS 207
            |....|.::||..:|:::|.|...:.....:.:||.:.|:. :..|:....||. ..|.|..|..
Human   145 DISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQF-EENGRKEIDIKKYARVEKIPGGI 208

  Fly   208 ARESVLIPGYALNCTIASQQMPKKIVNAKIACLDFSLQKTKMKMGVQVLINDPDKLEAIRARELD 272
            ..:|.::.|..:|..:...:|.:.|.|.:|..||.||:..|.:....:.|...:....|...|.:
Human   209 IEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEE 273

  Fly   273 ITKERINMILGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKATGAAFITSLTNM 337
            ..::....|:....:||:...|:.||...|.:.|...|:|||:|:|...||:|.||..::.
Human   274 YIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSR---- 334

  Fly   338 DGEESFDASMVGEAAEVAQ-ERICDDELILIKGTKARAAASIILRGPNDFYCDEMERSVHDALCV 401
              .|......||..|.:.: ::|.|:....|...|...|.:|:|||.:.....|:||::.||:.|
Human   335 --PEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQV 397

  Fly   402 VKRVLESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVIPKTLSVNAAKDATDL 466
            .:.||...::|.|||..|.|::..|...:.::...||......|::|.|||:||..|.......|
Human   398 CRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRL 462

  Fly   467 VAKLRSYHNSSQTKPERSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKIKSLKFATEAAITILRID 531
            :..||:.|.....:      .| |::...|.:.|.|:.|:.||...|:::.|.|.|.|:.:||||
Human   463 LTSLRAKHTQENCE------TW-GVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRID 520

  Fly   532 DMI---KLNPEDKS 542
            |::   |...:|:|
Human   521 DIVSGHKKKGDDQS 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	171/528 (32%)
CCT3	NP_005989.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		4/7 (57%)
		chap_CCT_gamma	6..529	CDD:274085	171/527 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..545		3/9 (33%)