Protein Alignment CCT1 and Mkks

DIOPT Version :10

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_001008354.1
• Gene: Mkks / 311456
• RGDID: 1308814
• Length: 570
• Species: Rattus norvegicus
• Alignment Length: 586
• Identity: 125/586 - (21%)
• Similarity: 235/586 - (40%)
• Gaps: 99/586 - (16%)

  Fly    22 TQNVMAALSI-SNIVKSSLGPVGLDKMLVDDIGD-VTVTNDGATILRLLEVEHPAAKVLVELAQL 84
            ::.|.:.||: ..|:.|..||.|..|.|.:.:|. |..|:..:.:||.|.|.||..|||....|.
  Rat    19 SERVRSTLSVLKGIIASCYGPSGRLKQLHNGLGGCVCTTSQSSALLRNLSVTHPILKVLTSSVQN 83

  Fly    85 QDEEVGDGTTSVVILAAELLKNADELVKQKIHPTSIIS------GYRIAC--KEACKYISEHLTA 141
            ......|......||...|::|...:   .:.||:.|.      |..|:.  .|||.     ...
  Rat    84 HVCCFSDCGLFTAILCCNLIENIQRI---GLTPTTAIKLNKYLLGLSISYLKSEACS-----CRI 140

  Fly   142 PVDELGRDSLINIAKTSMSSK----IIGADAEFFSAMVVDAAQSVKITDPRGQAAYSI--KAINV 200
            |||.....:.:|:..:.::||    :...:.:...|:::.|   ..:|.|.......:  |:| :
  Rat   141 PVDFRSTHTFLNLVHSILTSKPACMLTRKEIDHIGALILKA---FLLTIPESAEERMVLGKSI-I 201

  Fly   201 LKAHGKSARESVLIPGYALNCTIASQQMPKKI--------VNAKIACLDFSLQKTKMKMGVQVLI 257
            :...|:...:|.::||..:.   ||:...:::        :...:.|...|...:....|..|:.
  Rat   202 VPLKGQQVTDSTVLPGLLIE---ASEVQLRRLLPTQKSSTLRVALFCASLSGDFSNAGEGTLVVH 263

  Fly   258 NDPDKLEAIRARELDITKERINMILGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKII 322
            .......|:..:.|::.::    ::...|::||....:.....::..|...:|:.||..:.::.:
  Rat   264 YQVSLENAVLEQLLNLGRQ----LVSDHVDLVLCQKVIHPSLKQFLSEHQIIAIDRVGVTLMEPL 324

  Fly   323 AKATGAAFITSLTNMDGEESFDASMVGEAAEVAQERICDDELILIKGTKARAAASIILRGPNDFY 387
            :|.|||..|.||      ....::..|...:|...|........:...:| ...|::|...||..
  Rat   325 SKVTGATPIGSL------YPIVSTTYGSVKDVRSARFGSKYFFHLLPNEA-TICSLLLCSRNDTA 382

  Fly   388 CDEMERSVHDALCVVKRVLESKKVVAGGGCVEAALSIYL----ENFATSL-----ASREQLAIA- 442
            .:|::.:...|:.|::..::...|:.||||||..|:.|:    .|.|.::     .|:.:|.||
  Rat   383 WEELKLTCQTAMHVLQLTIKEPWVLLGGGCVETHLAAYIRHKVHNEAEAIVRDDGCSQAELHIAT 447

  Fly   443 -EFAKSLLVIPKTLSVNAAKDATDLVAKLRSYHNSSQTKPERSDLKW--------TGL-----DL 493
             .|..:|    ::.:|:...|..:::..::..|..|......|...|        .||     :|
  Rat   448 EAFCSAL----ESAAVSLEHDGGEILIDMKYGHFWSCPADSASVGNWPDTLSRCGCGLYNSQEEL 508

  Fly   494 IEGVVRD------------NKKAG-----VLEPAMSKIKSLKFATEAAITILRIDDMIKLNPEDK 541
            ...|:|.            ...:|     .::...:|:..|:.|.|.|..||.:..:|    |||
  Rat   509 SWSVLRSTYHPFAPQTCLPQAASGSVSNLTVDSFTAKLSGLQVAVETANLILDLSYVI----EDK 569

  Fly   542 S 542
            :
  Rat   570 N 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	122/580 (21%)
Mkks	NP_001008354.1	Cpn60_TCP1	29..569	CDD:395068	120/573 (21%)