Protein Alignment CCT1 and Cct6a

DIOPT Version :10

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_001028856.1
• Gene: Cct6a / 288620
• RGDID: 1304763
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 139/547 - (25%)
• Similarity: 272/547 - (49%)
• Gaps: 32/547 - (5%)

  Fly     6 SPLSIAGTRQSGASVRTQNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLLEV 70
            :|.:.....|:..:|   |:.||..:.::::::|||.|..||||...||:.:|.||..:|..:::
  Rat     8 NPKAEVARAQAALAV---NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQI 69

  Fly    71 EHPAAKVLVELAQLQDEEVGDGTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACKYI 135
            :||.|.::.::|..||:..||||||.|::..||||.||..:.:.:||..|..|:..|.::|.:::
  Rat    70 QHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFL 134

  Fly   136 SEHLTAPVDELGRDSLINIAKTSMSSKIIGADAEFFSAMVVDAAQSVKITDPRGQAAYSIKAINV 200
            .:...:  .|:.|::||::|:||:.:|:....|:..:..|||:..:::..|    ....:..:.:
  Rat   135 EQVKVS--KEMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIRKKD----EPIDLFMVEI 193

  Fly   201 LKAHGKSARESVLIPGYALNCTIASQQMPKKIVNAKIACLDFSLQKTKMKMGVQVLINDPDKLEA 265
            ::...||..::.||.|..|:.......|.|::.||.|...:.||:..|.::.........::.|.
  Rat   194 MEMKHKSETDTSLIRGLVLDHGARHPDMKKRVENAYILTCNVSLEYEKTEVNSGFFYKSAEEREK 258

  Fly   266 IRARELDITKERINMILGTGVN---------VVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKI 321
            :...|....::|:..|:.....         ||:...|:|...:....:.|.:|:||.|:.:::.
  Rat   259 LVKAERKFIEDRVKKIVELKKKVCGDSDKGFVVINQKGIDPFSLDALAKEGIVALRRAKRRNMER 323

  Fly   322 IAKATGAAFITSLTNMDGEESFDASMVGEAAEVAQERICDDELILIKGTKARAAASIILRGPNDF 386
            :..|.|...:.|..:::.:      .:|.|..|.:..:.:::...|:......:.:::::|||..
  Rat   324 LTLACGGIALNSFDDLNPD------CLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLVKGPNKH 382

  Fly   387 YCDEMERSVHDALCVVKRVLESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVI 451
            ...:::.::.|.|..||..::...||.|.|.||.||:..|..:..|:..|.||.:..||.:||:|
  Rat   383 TLTQIKDAIRDGLRAVKNAIDDGCVVPGAGAVEVALAEALIKYKPSVKGRAQLGVQAFADALLII 447

  Fly   452 PKTLSVNAAKDATDLVAKLRSYHNSSQTKPERSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKIKS 516
            ||.|:.|:..|..:.:.|:::.|:.|.        :..|:||..|......:.||.:....|.:.
  Rat   448 PKVLAQNSGFDLQETLVKVQAEHSESG--------QLVGVDLNTGEPMVAAEMGVWDNYCVKKQL 504

  Fly   517 LKFATEAAITILRIDDMIKLNPEDKSG 543
            |...|..|..||.:|::::.......|
  Rat   505 LHSCTVIATNILLVDEIMRAGMSSLKG 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	137/534 (26%)
Cct6a	NP_001028856.1	chap_CCT_zeta	3..530	CDD:274088	138/544 (25%)