Protein Alignment CCT1 and Cct8l1

DIOPT Version :10

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_941023.1
• Gene: Cct8l1 / 242891
• MGIID: 2685289
• Length: 562
• Species: Mus musculus
• Alignment Length: 518
• Identity: 122/518 - (23%)
• Similarity: 235/518 - (45%)
• Gaps: 46/518 - (8%)

  Fly    27 AALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLLEVEHPAAKVLVELAQLQDEEVGD 91
            ||.::::|::|..||.|..|.||...|:...|...|.||:.|::|||||:.:.||||.|.|..||
Mouse    48 AAQTLASIIRSCYGPFGRQKFLVTAKGETVCTGHAAAILKALDLEHPAAQFVQELAQTQVENAGD 112

  Fly    92 GTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACKYISEHLTA----PVDELG--RD- 149
            ||..||:|...||:.|..|:...:.||.:...:..|..|.       |||    .:..||  .|
Mouse   113 GTVFVVLLTEALLEQAHYLLWAGLTPTQLREAFATATAEV-------LTALPSLAIRSLGPLEDP 170

  Fly   150 --SLINIAKTSMSSKIIGADAEFFSAMVVDAAQSVKITDPRGQAAYSIKAINVLKAHGKSARESV 212
              :|.::..|...|     ::::.:.:|..|....:  :|.|  ::..::|.|....|....:|.
Mouse   171 SWALYSVISTHTLS-----NSDYLTKLVAQACWVSR--EPNG--SFKPESIVVCVLQGGKLTDSR 226

  Fly   213 LIPGYALNCTIASQQMPKKIVNAKIACLDFSLQKTKMKMGVQVLINDPDKLEAIRARELDITKER 277
            :.||.|:...:..|: .:.:.:|::|..:.....|.........:::|::|...|.:...:.||
Mouse   227 IFPGVAIAGKLCGQK-TEVLGDARVALFNCPFGPTNPFTLATPRLSNPEELLRFRKQTEQVEKE- 289

  Fly   278 INMILGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKATGAAFITSLTNMDGEES 342
            |..:....:||.:|.|.|::..:......|.|.::...:.::..:::..|...:..:
Mouse   290 IAQLAIMDINVAVVLGEVNEKSVDQANYCGIMVIQAKSRKEIVYLSEKLGTPLLGRV-------- 346

  Fly   343 FDASMVGEAAEVAQERICDDELILIKGTKARAA-ASIILRGPNDFYCDEMERSVHDALCVVKRVL 406
            ......|:..:|.::...|..:::.:.....|. .|::||||........|::|:..:....::.
Mouse   347 LPPLEPGKCHKVYRKEFGDTAVVMFEWEHEIAPFLSVVLRGPTIQGLRVAEQAVYYGIDAFSQLC 411

  Fly   407 ESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVIPKTLSVNAAKDATDLVAKLR 471
            :..:::.|.|..|.||:..|.:..:.|:....||...||::|..:||||:.||...|..::|:|.
Mouse   412 QDPRLLPGAGATEMALAKMLVDKGSRLSGPNGLAFQAFAQALSSLPKTLAENAGLAAQSVMAELS 476

  Fly   472 SYHNSSQTKPERSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKIKSLKFATEAAITILRIDDMI 534
            .:|.:.      :.....|.|.:..|..:    |:.:...:|.:.|:...|....::.:|.:|
Mouse   477 GFHQAG------NFFVGVGTDGLVNVTHE----GIWDILRTKAQGLQAVAELVQQLVTVDQII 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	122/518 (24%)
Cct8l1	NP_941023.1	Cpn60_TCP1	52..532	CDD:395068	120/514 (23%)