Protein Alignment CCT1 and cct-6

DIOPT Version :10

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_741153.1
• Gene: cct-6 / 175819
• WormBaseID: WBGene00000381
• Length: 539
• Species: Caenorhabditis elegans
• Alignment Length: 532
• Identity: 141/532 - (26%)
• Similarity: 260/532 - (48%)
• Gaps: 47/532 - (8%)

  Fly    24 NVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLLEVEHPAAKVLVELAQLQDEE 88
            |:..|..:.::::|:|||.|..||||...||:.:|.||..:|..:.::||.|.::.:.:..||:.
 Worm    23 NISGARGLQDVMRSNLGPKGTLKMLVSGAGDIKLTKDGNVLLHEMAIQHPTASMIAKASTAQDDV 87

  Fly    89 VGDGTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACKYISE-HLTAPVDELGRDSLI 152
            .||||||.|:|..||||.|:.||.:.:||..:..|:..|..:..:.:.: ...|||:   ||.|:
 Worm    88 TGDGTTSTVLLIGELLKQAESLVLEGLHPRIVTEGFEWANTKTLELLEKFKKEAPVE---RDLLV 149

  Fly   153 NIAKTSMSSKIIGADAEFFSAMVVDAAQSVKITDPRGQAAYSIKAINVLKAHGKSARESVLIPGY 217
            .:.:|::.:|:....|:..:..||||..:::    |......:..:..::.|..|..::.|:.|.
 Worm   150 EVCRTALRTKLHQKLADHITECVVDAVLAIR----RDGEEPDLHMVEKMEMHHDSDMDTTLVRGL 210

  Fly   218 ALNCTIASQQMPKKIVNAKIACLDFSLQKTKMKMGVQVLINDPDKLEAIRARELDITKERINMIL 282
            .|:.......||:.:.:|.|...:.||:..|.::...:......:.||:.|.|.:....|::.|:
 Worm   211 VLDHGARHPDMPRHVKDAYILTCNVSLEYEKTEVNSGLFYKTAKEREALLAAEREFITRRVHKII 275

  Fly   283 ----------GTGVN---VVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKATGAAFITSL 334
                      ..|.|   ||:...|:|...:......|.:|:||.|:.:::.:..|.|...:.|:
 Worm   276 ELKKKVIDNSPDGKNKGFVVINQKGIDPPSLDLLASEGILALRRAKRRNMERLQLAVGGEAVNSV 340

  Fly   335 TNMDGEESFDASMVGEAAEVAQERICDDELILIKGTKARAAASIILRGPNDFYCDEMERSVHDAL 399
            .::..|:      :|.|..|.:..:.:::...|:..:|..:.:::::|||.....:::.::||.|
 Worm   341 DDLTPED------LGWAGLVYEHSLGEEKYTFIEECRAPKSVTLLIKGPNKHTITQIKDAIHDGL 399

  Fly   400 CVVKRVLESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVIPKTLSVNAAKDAT 464
            ..|...:..|.|:.|....|.|..:.|:....:|..|.:|....||::||||||||:||...||.
 Worm   400 RAVFNTIVDKAVLPGAAAFEIAAYVMLKKDVENLKGRAKLGAEAFAQALLVIPKTLAVNGGYDAQ 464

  Fly   465 DLVAKLRSYHNSSQTKPERSDLKWTGLDLIEGVVRDNKKAGVLEP------AMSKIKSLKFATEA 523
            :.:.||  ....:...|:.:    .||||..|        |.:||      ...|..|:..||..
 Worm   465 ETLVKL--IEEKTAAGPDIA----VGLDLETG--------GAVEPQGIWDNVTVKKNSISSATVL 515

  Fly   524 AITILRIDDMIK 535
            |..:|.:|::::
 Worm   516 ACNLLLVDEVMR 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	141/532 (27%)
cct-6	NP_741153.1	chap_CCT_zeta	3..534	CDD:274088	141/532 (27%)