Protein Alignment CCT1 and LOC1278824

DIOPT Version :10

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: XP_318461.2
• Gene: LOC1278824 / 1278824
• VectorBaseID: AGAMI1_000628
• Length: 573
• Species: Anopheles gambiae
• Alignment Length: 627
• Identity: 130/627 - (20%)
• Similarity: 236/627 - (37%)
• Gaps: 185/627 - (29%)

  Fly     1 MSTLASPLSIAGTRQSGAS------VRTQNVMAALSISNI------VKSSLGPVGLDKMLVDDIG 53
            |..|.:.|.:|..||..||      ||....:.||.:..:      |..::||.|.:.:|....|
Mosquito     1 MFRLPTVLRVAAARQVAASRGYAKDVRFGPEVRALMLQGVDVLADAVAVTMGPKGRNVILEQSWG 65

  Fly    54 DVTVTNDGATILRLLEV----EHPAAKVLVELAQLQDEEVGDGTTSVVILAAELLKNADELVKQK 114
            ...:|.||.|:.:.:|:    ::..||::.::|...:||.|||||:..:||..:.|...|.:.:.
Mosquito    66 SPKITKDGVTVAKGIELKCKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISKG 130

  Fly   115 IHPTSIISGYRIA---CKEACKYISEHLTAP----------------VDELGRDSLINIAK---- 156
            .:|..|..|..:|   .||..|.:|..:..|                :.:|..:::..:.|
Mosquito   131 ANPVEIRRGVMLAVDTVKEHLKTLSRKVNTPEEIAQVATISANGDRAIGDLISEAMKRVGKEGVI 195

  Fly   157 TSMSSKIIGADAE----------FFSAMVVDAAQSVKITDPRGQAAYSIKAINVLKAHGKSARES 211
            |....|.:..:.|          :.|...:::::..|:........:|.|.|:.:::
Mosquito   196 TVKDGKTLNDELEVIEGMKFDRGYISPYFINSSKGAKVEFQDALVLFSEKKISTVQS-------- 252

  Fly   212 VLIPGYALNCTIASQQMPKKIVNAKIACLDF------SLQKTKMKMGVQVLINDPDKLEAIRARE 270
             :||...:    |:||....::.|:    |.      :|...::|:|:||        .|::|.
Mosquito   253 -IIPALEM----ANQQRKPLVIIAE----DVDGEALSTLVVNRLKIGLQV--------AAVKAP- 299

  Fly   271 LDITKERINMILGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKATGAAFITSLT 335
                        |.|.|                           :||.|..:|.:||........
Mosquito   300 ------------GFGDN---------------------------RKSTLSDMAISTGGIVFGDDA 325

  Fly   336 NMDGEESFDASMVGEAAEVAQERICDDELILIKG------------------------------- 369
            |:...|....|.:|:..|:.   |..|:.:|:||
Mosquito   326 NLVKLEDVQLSDLGQVGEIT---ITKDDCLLLKGRGKQEDVNRRADQIRDQIAETTSEYEKEKLQ 387

  Fly   370 -TKARAAASI-ILR--GPNDFYCDEMERSVHDALCVVKRVLESKKVVAGGGCVEAALSIYLENFA 430
             ..||.::.: :|:  |.::...:|.:..|:||||..:..:| :.:|.|||......:..|.|..
Mosquito   388 ERLARLSSGVAVLKVGGSSEVEVNEKKDRVNDALCATRAAVE-EGIVPGGGTALIRCAPALANLK 451

  Fly   431 TSLASREQLAIAEFAKSLLVIPKT-LSVNAAKDATDLVAKLRSYHNSSQTKPERSDLKWT-GLDL 493
            .  |:.:|....|..:..|.:|.| ::.||..|.:.:|||:             .:||.. |.|.
Mosquito   452 G--ANEDQNTGIEIVRRALRMPCTQIAKNAGVDGSVVVAKV-------------EELKGDFGYDA 501

  Fly   494 IEGVVRDNKKAGVLEPA---------MSKIKSLKFATEAAIT 526
            :.....:..:.|:::|.         .|.:.||....||.:|
Mosquito   502 LNNEYVNMIEKGIIDPTKVVRTALSDASGVASLLTTAEAVVT 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	126/616 (20%)
LOC1278824	XP_318461.2	GroEL	24..544	CDD:239460	122/604 (20%)