Protein Alignment CCT1 and Cct8

DIOPT Version :10

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_033970.3
• Gene: Cct8 / 12469
• MGIID: 107183
• Length: 548
• Species: Mus musculus
• Alignment Length: 542
• Identity: 170/542 - (31%)
• Similarity: 279/542 - (51%)
• Gaps: 53/542 - (9%)

  Fly    23 QNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLLEVEHPAAKVLVELAQLQDE 87
            :|:.|...::...:::.||.|::||:::.:..:.||||.|||||.|||:|||||::|..:.:|::
Mouse    31 RNIQACKELAQTTRTAYGPNGMNKMVINRLEKLFVTNDAATILRELEVQHPAAKMIVMASHMQEQ 95

  Fly    88 EVGDGTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACKYISEHLTAPVDEL-GRDSL 151
            ||||||..|::.|..||:.|:||::..:..:.:||||.||||:|.:.:.|.:......| ..|.:
Mouse    96 EVGDGTNFVLVFAGALLELAEELLRIGLSVSEVISGYEIACKKAHEILPELVCCSAKNLRDVDEV 160

  Fly   152 INIAKTSMSSKIIGADAEFFSAMVVDAAQSVKITDPRGQAAYSIKAINVLKAHGKSARESVLIPG 216
            .::.:||:.||..|::. |.:.::..|.  |.|....|.  :::..|.|.|..|.....|.::.|
Mouse   161 SSLLRTSIMSKQYGSET-FLAKLIAQAC--VSIFPDSGN--FNVDNIRVCKILGSGIYSSSVLHG 220

  Fly   217 YALNCTIASQQMPKK--------IVNAKIA---C-LDFSLQKTKMKMGVQVLINDPDKLEAIRAR 269
            ...          ||        :.:||||   | .|..:.:||   |. |||...::|......
Mouse   221 MVF----------KKETEGDVTSVKDAKIAVYSCPFDGMITETK---GT-VLIKTAEELMNFSKG 271

  Fly   270 ELDITKERINMILGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKATGAAFITSL 334
            |.::...::..|.|||.||::..|.|.|:.:.|..:...|.||...|.||:.:.|..||..:..|
Mouse   272 EENLMDAQVKAIAGTGANVIVTGGKVADIALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPKL 336

  Fly   335 TNMDGEESFDASMVGEAAEVAQERICDDELILIKGTKARAAAS-IILRGPNDFYCDEMERSVHDA 398
            |....||      :|....|....:.|.::::.|..|...|.| |:|||..|...|::||:|.|.
Mouse   337 TPPVQEE------MGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDG 395

  Fly   399 LCVVKRVLESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVIPKTLSVNAAKDA 463
            :...|.:...|::|.|||..|..|:..:.::..:....||.||.:||::...||:.|:.|:...|
Mouse   396 VNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKA 460

  Fly   464 TDLVAKLRSYHNSSQTKPERSDLKWTGLDLIEGV--VRDNKKAGVLEPAMSKIKSLKFATEAAIT 526
            .::::||.|.|....        |..|||:...|  |:|..:|.:|:..:.|..::|.||.||:|
Mouse   461 NEVISKLYSVHQEGN--------KNVGLDIEAEVPAVKDMLEASILDTYLGKYWAIKLATNAAVT 517

  Fly   527 ILRIDDMIKL----NPEDKSGK 544
            :||:|.:|..    .|:..|||
Mouse   518 VLRVDQIIMAKPAGGPKPPSGK 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	166/534 (31%)
Cct8	NP_033970.3	chap_CCT_theta	10..539	CDD:274087	168/540 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	529..548		4/11 (36%)