Protein Alignment CCT1 and Cct7

DIOPT Version :10

• Sequence 1: NP_524450.2
• Gene: CCT1 / 42649
• FlyBaseID: FBgn0003676
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_031664.3
• Gene: Cct7 / 12468
• MGIID: 107184
• Length: 544
• Species: Mus musculus
• Alignment Length: 535
• Identity: 191/535 - (35%)
• Similarity: 289/535 - (54%)
• Gaps: 31/535 - (5%)

  Fly    12 GTRQS-GASVRTQNVMAALSISNIVKSSLGPVGLDKMLVDDIGDVTVTNDGATILRLLEVEHPAA 75
            ||..| |......|:.|...|:..|:::|||.|:||::||..|..|::|||||||:||:|.||||
Mouse    12 GTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATILKLLDVVHPAA 76

  Fly    76 KVLVELAQLQDEEVGDGTTSVVILAAELLKNADELVKQKIHPTSIISGYRIACKEACKYISEHLT 140
            |.||::|:.||.|||||||||.:||||.||.....|::.:||..||..:|.|.:.|...|.| :.
Mouse    77 KTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVNKIKE-IA 140

  Fly   141 APVDELG----RDSLINIAKTSMSSKIIGADAEFFSAMVVDAAQSVKITDPRGQAAYSIKAINVL 201
            ..|.:..    |..|...|.|::|||:|.....||:.|||||   |.:.|...|    :|.|.:.
Mouse   141 VTVKKQDKVEQRKMLEKCAMTALSSKLISQQKVFFAKMVVDA---VMMLDELLQ----LKMIGIK 198

  Fly   202 KAHGKSARESVLIPGYALNCTIA---SQQMPKKIVNAKIACLDFSLQKTKMKMGVQVLINDPDKL 263
            |..|.:..||.|:.|.|...|.:   .:..|||..|.|||.|:..|:....|...::.::..:..
Mouse   199 KVQGGALEESQLVAGVAFKKTFSYAGFEMQPKKYKNPKIALLNVELELKAEKDNAEIRVHTVEDY 263

  Fly   264 EAIRARELDITKERINMILGTGVNVVLVSGGVDDLCMKYFVEAGAMAVRRVKKSDLKIIAKATGA 328
            :||...|.:|..:::..|..:|..|:|....:.|:..:||.:.......||.:.|||....|.|.
Mouse   264 QAIVDAEWNILYDKLEKIHQSGAKVILSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMACGG 328

  Fly   329 AFITSLTNMDGEESFDASMVGEAAEVAQERICDDELILIKGTKARAAASIILRGPNDFYCDEMER 393
            :..||:      .:....::|......:.:|..:......|.......:|||||..:.:.:|.||
Mouse   329 SIQTSV------NALVPDVLGHCQVFEETQIGGERYNFFTGCPKAKTCTIILRGGAEQFMEETER 387

  Fly   394 SVHDALCVVKRVLESKKVVAGGGCVEAALSIYLENFATSLASREQLAIAEFAKSLLVIPKTLSVN 458
            |:|||:.:|:|.:::..||||||.:|..||.||.:::.::..::||.|..:||:|.:||:.|..|
Mouse   388 SLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDN 452

  Fly   459 AAKDATDLVAKLRSYHNSSQTKPERSDLKWTGLDLIEGVVRDNKKAGVLEPAMSKIKSLKFATEA 523
            |..|||:::.|||:.|....        .|.|:|:....:.||.:|.|.||||.:|.:|..|:||
Mouse   453 AGFDATNILNKLRARHAQGG--------MWYGVDINNENIADNFQAFVWEPAMVRINALTAASEA 509

  Fly   524 AITILRIDDMIKLNP 538
            |..|:.:|:.|| ||
Mouse   510 ACLIVSVDETIK-NP 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT1	NP_524450.2	TCP1_alpha	12..538	CDD:239451	189/533 (35%)
Cct7	NP_031664.3	TCP1_eta	5..525	CDD:239456	191/535 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	523..544		1/1 (100%)