Protein Alignment: lqfR and CLINT1

• Sequence 1: NP_732736.2
• Gene: lqfR
• FlyBaseID: FBgn0261279
• Length: 1415
• Species: Drosophila melanogaster
• Sequence 2: NP_001182484.1
• Gene: CLINT1
• HGNCID: 23186
• Length: 643
• Species: Homo sapiens
• Alignment Length: 641
• Identity: 232/642 (36%)
• Similarity: 307/642 (48%)
• Gaps: 157/642 (24%)

  Fly     6 ISMWKVRELADKVTNVVMNYTETEGKVREATNDDPWGPTGPLMQELAYSTFSYETFPEVMSMLWK 70
            ::|||||||.||.|||||||:|.|.|||||||||||||:|.||.|:|.:||.||.|||:|:|||.
Human     2 LNMWKVRELVDKATNVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWS 66

  Fly    71 RMLQDNKTNWRRTYKSLLLLNYLVRNGSERVVTSSREHIYDLRSLENYTFTDEGGKDQGINVRHK 135
            |||:|||.||||.|||||||.||:||||||||||:|||||||||||||.|.||.|||||||:|.|
Human    67 RMLKDNKKNWRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQK 131

  Fly   136 VRELIDFIQDDDRLREERKKAKKNKDKYIGMSSDAMGMRSGGYSGYSGGSGGGGGGSGGYNDGDY 200
            |:||::|.||||||||||||||||||||:|:|||::               ||...|..| |.:.
Human   132 VKELVEFAQDDDRLREERKKAKKNKDKYVGVSSDSV---------------GGFRYSERY-DPEP 180

  Fly   201 RSSRGDNWYSDKSA-----------DKDRYEDDDT--------HYDGEREGSDSDSPSPRRNYRY 246
            :|...:.|..:|||           ||.....|||        ..|.....||||.....|
Human   181 KSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEKKAR---- 241

  Fly   247 NDRASPAEVASEAKPSSLNMNIRSKTVSSPVSKQPTSTASAKPALSQKKIDLGAAANF--GKPAP 309
            ..|:...|...|.:      .:.:|.:....:.:.|:|...:.|...|.|||||||::  .|.:|
Human   242 RGRSPKGEFKDEEE------TVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASP 300

  Fly   310 GGAAGIHSPTHRDTPTSVDLMGGASPSPSTSKANNNTQSNNNDLLDDLFKTCSPPPGQEKTLNSA 374
            ...|..|:| .....|||       ||..:|          .||: |||
Human   301 DQNASTHTP-QSSVKTSV-------PSSKSS----------GDLV-DLF---------------- 330

  Fly   375 AVIVDDDDDFNPRASDASQQEFGDFASAFGQPSAGSTISEPPSTGLVPAANDEFADFAAFQGSTT 439
                    |...:::..|...||.||. ||..:|..:.   ||.....:.|.:|.|::||..:.:
Human   331 --------DGTSQSTGGSADLFGGFAD-FGSAAASGSF---PSQVTATSGNGDFGDWSAFNQAPS 383

  Fly   440 STSALDGNLLKTAT------------------PANDSFDLFNSAPTSTAAATTATDL-------- 478
            ...|..|....:|:                  .|::|.|||:...:|.|..|::..:
Human   384 GPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTN 448

  Fly   479 LAGLGDLSIHQSMPM-----------------------AVEEQLASS-ND------------SMS 507
            ..||| |.:.:|.|:                       :|.:.|.|: :|            .|.
Human   449 TVGLG-LPMSRSQPLQNVSTVLQKPNPLYNQNTDMVQKSVSKTLPSTWSDPSVNISLDNLLPGMQ 512

  Fly   508 SASPQPPSEAMRLAFSKAQKQLRDLMQVQSASAVAQVAAILGELHNSNALPGFTTP 563
            .:.||.||....:.....|:.:..:.|...|..::..:.:|.....:|||.|...|
Human   513 PSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLSSPSNMLPVRPQTNALIGGPMP 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lqfR	NP_732736.2	ENTH_epsin	27..150	CDD:239627	95/123 (77%)
		DUF4045	<226..459	CDD:289995	58/253 (23%)
		Telomere_reg-2	1072..1184	CDD:287202
CLINT1	NP_001182484.1	ENTH_epsin	23..146	CDD:239627	95/123 (77%)
		Nucleoporin_FG	329..407	CDD:316182	21/106 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C317109789
eggNOG	1	0.900				E1_KOG2057
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000				H133740
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0004790
OrthoInspector	1	1.000				T1073217
orthoMCL	1	0.900				OOG5_128219
Panther	1	1.100			LDO	PTHR12276
Phylome	1	0.910		0.750	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R2102
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.770