Protein Alignment lqfR and CLINT1

DIOPT Version :9

• Sequence 1: NP_732736.2
• Gene: lqfR / 42632
• FlyBaseID: FBgn0261279
• Length: 1415
• Species: Drosophila melanogaster
• Sequence 2: NP_001182484.1
• Gene: CLINT1 / 9685
• HGNCID: 23186
• Length: 643
• Species: Homo sapiens
• Alignment Length: 641
• Identity: 232/641 - (36%)
• Similarity: 307/641 - (47%)
• Gaps: 157/641 - (24%)

  Fly     6 ISMWKVRELADKVTNVVMNYTETEGKVREATNDDPWGPTGPLMQELAYSTFSYETFPEVMSMLWK 70
            ::|||||||.||.|||||||:|.|.|||||||||||||:|.||.|:|.:||.||.|||:|:|||.
Human     2 LNMWKVRELVDKATNVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWS 66

  Fly    71 RMLQDNKTNWRRTYKSLLLLNYLVRNGSERVVTSSREHIYDLRSLENYTFTDEGGKDQGINVRHK 135
            |||:|||.||||.|||||||.||:||||||||||:|||||||||||||.|.||.|||||||:|.|
Human    67 RMLKDNKKNWRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQK 131

  Fly   136 VRELIDFIQDDDRLREERKKAKKNKDKYIGMSSDAMGMRSGGYSGYSGGSGGGGGGSGGYNDGDY 200
            |:||::|.||||||||||||||||||||:|:|||::               ||...|..| |.:.
Human   132 VKELVEFAQDDDRLREERKKAKKNKDKYVGVSSDSV---------------GGFRYSERY-DPEP 180

  Fly   201 RSSRGDNWYSDKSA-----------DKDRYEDDDT--------HYDGEREGSDSDSPSPRRNYRY 246
            :|...:.|..:|||           ||.....|||        ..|.....||||.....|
Human   181 KSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEKKAR---- 241

  Fly   247 NDRASPAEVASEAKPSSLNMNIRSKTVSSPVSKQPTSTASAKPALSQKKIDLGAAANF--GKPAP 309
            ..|:...|...|.:      .:.:|.:....:.:.|:|...:.|...|.|||||||::  .|.:|
Human   242 RGRSPKGEFKDEEE------TVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASP 300

  Fly   310 GGAAGIHSPTHRDTPTSVDLMGGASPSPSTSKANNNTQSNNNDLLDDLFKTCSPPPGQEKTLNSA 374
            ...|..|:| .....|||       ||..:|          .||: |||
Human   301 DQNASTHTP-QSSVKTSV-------PSSKSS----------GDLV-DLF---------------- 330

  Fly   375 AVIVDDDDDFNPRASDASQQEFGDFASAFGQPSAGSTISEPPSTGLVPAANDEFADFAAFQGSTT 439
                    |...:::..|...||.||. ||..:|..:.   ||.....:.|.:|.|::||..:.:
Human   331 --------DGTSQSTGGSADLFGGFAD-FGSAAASGSF---PSQVTATSGNGDFGDWSAFNQAPS 383

  Fly   440 STSALDGNLLKTAT------------------PANDSFDLFNSAPTSTAAATTATDL-------- 478
            ...|..|....:|:                  .|::|.|||:...:|.|..|::..:
Human   384 GPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTN 448

  Fly   479 LAGLGDLSIHQSMPM-----------------------AVEEQLASS-ND------------SMS 507
            ..||| |.:.:|.|:                       :|.:.|.|: :|            .|.
Human   449 TVGLG-LPMSRSQPLQNVSTVLQKPNPLYNQNTDMVQKSVSKTLPSTWSDPSVNISLDNLLPGMQ 512

  Fly   508 SASPQPPSEAMRLAFSKAQKQLRDLMQVQSASAVAQVAAILGELHNSNALPGFTTP 563
            .:.||.||....:.....|:.:..:.|...|..::..:.:|.....:|||.|...|
Human   513 PSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLSSPSNMLPVRPQTNALIGGPMP 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lqfR	NP_732736.2	ENTH_epsin	27..150	CDD:239627	94/122 (77%)
		DUF4045	<226..459	CDD:289995	57/252 (23%)
		Telomere_reg-2	1072..1184	CDD:287202
CLINT1	NP_001182484.1	ENTH_EpsinR	24..149	CDD:340786	96/124 (77%)
		Nucleoporin_FG	329..407	CDD:372653	21/105 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141860
Domainoid	1	1.000	206	1.000	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG2057
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H133740
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005493
OrthoInspector	1	1.000	-	-		oto91013
orthoMCL	1	0.900	-	-		OOG6_103183
Panther	1	1.100	-	-	LDO	PTHR12276
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2102
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.770