Protein Alignment CAH8 and CA11

DIOPT Version :10

• Sequence 1: NP_651033.2
• Gene: CAH8 / 42625
• FlyBaseID: FBgn0038956
• Length: 303
• Species: Drosophila melanogaster
• Sequence 2: NP_001208.2
• Gene: CA11 / 770
• HGNCID: 1370
• Length: 328
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 69/258 - (26%)
• Similarity: 113/258 - (43%)
• Gaps: 42/258 - (16%)

  Fly    45 GSEQSPIAISRRKAIPLNLPPLIFALYDEFFDEL----------VTIRNSGHTVEF-KVPTTIYG 98
            |..|||:.:..::           .|||.|...|          .|:.|:|..|.| ..|..:..
Human    65 GKRQSPVDVELKR-----------VLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVN 118

  Fly    99 VKPYVTGGLLRDCYDAEAVHFHWGSPESKGSEHLLNGRRFDLEMHIVHRNTK-YLNLEEAVKYSD 162
                |:||.|...:....:...:|:.:..||||.:|.:.|..|:.::|.|.: |.|...|.:..:
Human   119 ----VSGGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPN 179

  Fly   163 GVTVLAVLFKVV-RSGPFFYQPGLSEIFS--SLLHLGNFNASYTVQERLTLGSLLGSLDRGNFYT 224
            |:.:|::...|. .|.||     ||.:.:  ::..:...|.:|.:|: |:|..|..  :...|.|
Human   180 GLAILSLFVNVASTSNPF-----LSRLLNRDTITRISYKNDAYFLQD-LSLELLFP--ESFGFIT 236

  Fly   225 YKGSLTTPPCSPVVQWHVFGEVLPISHQDLPKF----WNLRDERGRPLLKNFRPLQSQENRLI 283
            |:|||:|||||..|.|.:....|.|:...:...    .|...:..:.|..|.||||...:|.:
Human   237 YQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRAL 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH8	NP_651033.2	Carb_anhydrase	33..286	CDD:459707	69/258 (27%)
CA11	NP_001208.2	alpha_CARP_X_XI_like	48..304	CDD:239395	69/258 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..328		0/1 (0%)