Protein Alignment CAH8 and CA6

DIOPT Version :10

• Sequence 1: NP_651033.2
• Gene: CAH8 / 42625
• FlyBaseID: FBgn0038956
• Length: 303
• Species: Drosophila melanogaster
• Sequence 2: XP_011540386.1
• Gene: CA6 / 765
• HGNCID: 1380
• Length: 324
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 103/285 - (36%)
• Similarity: 144/285 - (50%)
• Gaps: 35/285 - (12%)

  Fly    14 LFLLPFAANFRSTDFDYK----SPERWPEKYPNCGGSEQSPIAISRRKAIPLN--LPPLIFALYD 72
            ||||...|...| |:.|.    ....||:.||.|||..||||.:.|.| :..|  |..|....|:
Human    14 LFLLGGQAQHVS-DWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTK-VRYNPSLKGLNMTGYE 76

  Fly    73 EFFDELVTIRNSGHTVEFKVPTTIYGVKPYVTGGLLRDCYDAEAVHFHWG--SPESKGSEHLLNG 135
            ....|...: |:||||:..:|:|   ::..|..|.:   |.|:.:|||||  |.|..||||.::|
Human    77 TQAGEFPMV-NNGHTVQISLPST---MRMTVADGTV---YIAQQMHFHWGGASSEISGSEHTVDG 134

  Fly   136 RRFDLEMHIVHRNTKYLNLEEAVKYSDGVTVLAVLFKVVRSGP--FFYQPGLSEIFSSLLHLGNF 198
            .|..:|:||||.|:||.:.:.|....||:.|||. |..|::.|  .:|...:|       ||.|.
Human   135 IRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAA-FVEVKNYPENTYYSNFIS-------HLANI 191

  Fly   199 NASYTVQERLTLGSL--LGSLDRG--NFYTYKGSLTTPPCSPVVQWHVFGEVLPISHQDLPKFWN 259
              .|..| |.||..|  ...|.|.  ::|||.||||||||:..|.|.|..:.:.:|...:.|..|
Human   192 --KYPGQ-RTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLEN 253

  Fly   260 -LRDERGRPLLKNFRPLQSQENRLI 283
             |.|.|.:.:..::|..|...:|::
Human   254 SLLDHRNKTIHNDYRRTQPLNHRVV 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH8	NP_651033.2	Carb_anhydrase	33..286	CDD:459707	95/262 (36%)
CA6	XP_011540386.1	alpha_CA_VI	35..283	CDD:239399	95/263 (36%)