Protein Alignment CAH8 and CA10

DIOPT Version :10

• Sequence 1: NP_651033.2
• Gene: CAH8 / 42625
• FlyBaseID: FBgn0038956
• Length: 303
• Species: Drosophila melanogaster
• Sequence 2: NP_064563.1
• Gene: CA10 / 56934
• HGNCID: 1369
• Length: 328
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 75/268 - (27%)
• Similarity: 117/268 - (43%)
• Gaps: 62/268 - (23%)

  Fly    45 GSEQSPIAISRRKAIPLNLPPLIFALYDEFFDELVTIRNSGHTVEFKVPTTIYGVKPYV------ 103
            |..|||:.|.....|           :|.|...| .|...|.    ||..|:|....:|
Human    63 GKRQSPVNIETSHMI-----------FDPFLTPL-RINTGGR----KVSGTMYNTGRHVSLRLDK 111

  Fly   104 ------TGGLLRDCYDAEAVHFHWGSPESKGSEHLLNGRRFDLEMHIVHRNTK-YLNLEEAVKYS 161
                  :||.:...:..|.:..|:||.:|:||||||||:.|..|:.::|.|.: |.|:.||.|..
Human   112 EHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSP 176

  Fly   162 DGVTVLAVLFKVVRSGPFFYQPGLSEIFS--SLLHLGNFNASYTVQERLTLGSLLGSL--DRGNF 222
            :|:.|:::..||..|.    .|.|:.:.:  ::..:...|.:|.:|     |..:..|  :..:|
Human   177 NGLVVVSIFIKVSDSS----NPFLNRMLNRDTITRITYKNDAYLLQ-----GLNIEELYPETSSF 232

  Fly   223 YTYKGSLTTPPCSPVVQWHVFGEVLPISH----------QDLPK--FWNLRDERGRPLLKNFRPL 275
            .||.||:|.|||.....|.:..:.:.|:.          |:.|.  |.::.|        ||||:
Human   233 ITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSD--------NFRPV 289

  Fly   276 QSQENRLI 283
            |...||.|
Human   290 QPLNNRCI 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH8	NP_651033.2	Carb_anhydrase	33..286	CDD:459707	75/268 (28%)
CA10	NP_064563.1	alpha_CARP_X_XI_like	46..302	CDD:239395	75/268 (28%)