Protein Alignment CAH8 and CA14

DIOPT Version :10

• Sequence 1: NP_651033.2
• Gene: CAH8 / 42625
• FlyBaseID: FBgn0038956
• Length: 303
• Species: Drosophila melanogaster
• Sequence 2: NP_036245.1
• Gene: CA14 / 23632
• HGNCID: 1372
• Length: 337
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 92/265 - (34%)
• Similarity: 128/265 - (48%)
• Gaps: 23/265 - (8%)

  Fly    30 YKSP---ERWPEKYPNCGGSEQSPIAISRRK-AIPLNLPPLIFALYDEFFDELVTIRNSGHTVEF 90
            |:.|   :.||..||.||.:.||||.|.... ....:||.|....||:...|.:.:.|:||||:.
Human    24 YEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTVQL 88

  Fly    91 KVPTTIYGVKPYVTGGLLRDCYDAEAVHFHWGSPESK-GSEHLLNGRRFDLEMHIVHRNT-KYLN 153
            .:|:|:|      .|||.|. |.|..:|.|||...|. ||||.:|......|:||||.:: .|.:
Human    89 SLPSTLY------LGGLPRK-YVAAQLHLHWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDS 146

  Fly   154 LEEAVKYSDGVTVLAVLFKVVRSGPFFYQPGLSEIFSSLLHLGNFNASYTVQERLTLGSLLGSLD 218
            |.||.:...|:.||.:|.:|..:....|:..||.     ||........|......|..||.. .
Human   147 LSEAAERPQGLAVLGILIEVGETKNIAYEHILSH-----LHEVRHKDQKTSVPPFNLRELLPK-Q 205

  Fly   219 RGNFYTYKGSLTTPPCSPVVQWHVFGEVLPISHQDLPK----FWNLRDERGRPLLKNFRPLQSQE 279
            .|.::.|.||||||||...|.|.||.....||.:.|.|    .::..:|..:.|::|:|.||...
Human   206 LGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEEEPSKLLVQNYRALQPLN 270

  Fly   280 NRLIF 284
            .|::|
Human   271 QRMVF 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH8	NP_651033.2	Carb_anhydrase	33..286	CDD:459707	91/262 (35%)
CA14	NP_036245.1	alpha_CA_XII_XIV	29..278	CDD:239400	90/260 (35%)