Protein Alignment CAH8 and Car3

DIOPT Version :10

• Sequence 1: NP_651033.2
• Gene: CAH8 / 42625
• FlyBaseID: FBgn0038956
• Length: 303
• Species: Drosophila melanogaster
• Sequence 2: NP_031632.2
• Gene: Car3 / 12350
• MGIID: 88270
• Length: 260
• Species: Mus musculus
• Alignment Length: 282
• Identity: 81/282 - (28%)
• Similarity: 118/282 - (41%)
• Gaps: 64/282 - (22%)

  Fly    30 YKSPERWPEKYPNCGGSEQSPIAISRR--KAIPLNLPPLIFALYDEFFDELVTIRNSGHTVEFKV 92
            :..|:.|.|.||...|..||||.:..:  |..| :|.|. .|.||.  ....||.|:|.|.....
Mouse    10 HNGPDHWHELYPIAKGDNQSPIELHTKDIKHDP-SLQPW-SASYDP--GSAKTILNNGKTCRVVF 70

  Fly    93 PTTIYGVKPYVTGGLLRDCYDAEAVHFHWGSPESKGSEHLLNGRRFDLEMHIVHRNTKYLNLEEA 157
            ..| |. :..:.||.|...|.....|.||||.:..||||.::|.::..|:|:||.|.||....||
Mouse    71 DDT-YD-RSMLRGGPLSGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNTFGEA 133

  Fly   158 VKYSDGVTVLAVLFKVVRSGPFFYQPGLSEIFSSLLHLGNFNASYTVQERLTLGSLLGSLDR--- 219
            :|..||:.|:.:..|:.|                  ..|.|..            ||.:||:
Mouse   134 LKQPDGIAVVGIFLKIGR------------------EKGEFQI------------LLDALDKIKT 168

  Fly   220 -------------------GNFYTYKGSLTTPPCSPVVQWHVFGEVLPISHQDLPK----FWNLR 261
                               .:::||.||.|||||...:.|.:..|.:.:|...:.|    |.:..
Mouse   169 KGKEAPFTHFDPSCLFPACRDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFSSAE 233

  Fly   262 DERGRPLLKNFRPLQSQENRLI 283
            :|...||:.|:||.|..:.|::
Mouse   234 NEPPVPLVGNWRPPQPVKGRVV 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH8	NP_651033.2	Carb_anhydrase	33..286	CDD:459707	81/279 (29%)
Car3	NP_031632.2	alpha_CA_I_II_III_XIII	1..259	CDD:239393	81/282 (29%)
		Involved in proton transfer. /evidence=ECO:0000250|UniProtKB:P07451	64..67		1/2 (50%)