DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18596 and Mrm3

DIOPT Version :9

Sequence 1:	NP_651031.1	Gene:	CG18596 / 42622	FlyBaseID:	FBgn0038953	Length:	1136	Species:	Drosophila melanogaster
Sequence 2:	NP_899086.2	Gene:	Mrm3 / 67390	MGIID:	1914640	Length:	418	Species:	Mus musculus

Alignment Length:	257	Identity:	51/257 - (19%)
Similarity:	84/257 - (32%)	Gaps:	71/257 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   929 LKRALETFKRKQSVLIPELATSLAALNGNVQRKMNPVGDIYPESDFVVSNKARDDHELIVVASLI 993
            :|...|..|....::.|:....:.|       |.:||...|||:..         |..:.:..:.
Mouse   166 IKVKFEDIKDWSDLVTPQGIMGIFA-------KPDPVKMTYPETPL---------HHTLPLVLIC 214

  Fly   994 DKL---PNLGGLARTCEVLGVNTLILGLKS--QAEKSDFTNLSMTAEKTLNIL-----EVNPESL 1048
            |.|   .|||.:.|:....|.:.::| .|.  .|.:.......|.|...:.|:     |..|..|
Mouse   215 DNLRDPGNLGTILRSAAGAGCSKVLL-TKGCVDAWEPKVLRAGMGAHFQVPIVNNVEWETVPNHL 278

  Fly  1049 -----------AGFLLEKQMEGYKIVGAEQTAHSTNFVDFK--------------FPKKSI---- 1084
                       .|...:.||...  .|....|....|:.|.              .||..:
Mouse   279 PPDTRVYVADNCGHYAQVQMSDK--TGDRDWACDRRFLKFHKYEEDLDTKTRKDWLPKLEVQSYD 341

  Fly  1085 ---------LLLGHEKHGIPANLIGFLDYA----VEIPQYGLVRSLNVHVAGSLFIWEYCKQ 1133
                     :::|.|.||:....:...:..    :.||....|.|||..:|.|:.::|..:|
Mouse   342 LDWTGAPAAVVIGGETHGVSLESLQLAESTGGKRLLIPVVPGVDSLNSAMAASILLFEGKRQ 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18596	NP_651031.1	SpoU_methylase	986..1128	CDD:278985	37/193 (19%)
Mrm3	NP_899086.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	41..90
		SpoU	117..407	CDD:223640	51/257 (20%)
		SpoU_sub_bind	125..191	CDD:214943	5/31 (16%)
		SpoU_methylase	209..398	CDD:278985	37/191 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810