Protein Alignment CG18596 and LOC4576628

DIOPT Version :10

• Sequence 1: NP_651031.1
• Gene: CG18596 / 42622
• FlyBaseID: FBgn0038953
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: XP_001237715.3
• Gene: LOC4576628 / 4576628
• VectorBaseID: AGAMI1_003519
• Length: 1403
• Species: Anopheles gambiae
• Alignment Length: 1399
• Identity: 340/1399 - (24%)
• Similarity: 554/1399 - (39%)
• Gaps: 381/1399 - (27%)

  Fly    10 TATTTHAVVQAVETYIQN-QNLLGEIAELDDMLYDLVSMHKDN------------ELALKRV--- 58
            ||..|.||...::|:::. .:.|.||....|:|...:.:.|::            |..::|:
Mosquito   105 TANDTGAVHSELDTFVKRFDHELHEIPLYYDVLQTFLILAKEDTELMPHCCQLSGEQMVRRLTSE 169

  Fly    59 --------LQCIHNLLQTNSKYNVRFGPKVFHKLVSVVIADSREDSASRRQLVANLLVCVQLHIR 115
                    |.|:..||:.||        .::.:.:.|:.:             .||:
Mosquito   170 SKTIRMKALACLQTLLEFNS--------NLYGQWLCVLQS-------------PNLM-------- 205

  Fly   116 KFPRIEAKFVL--QQLWSLSQSNERQPHAAQILV--HLFDDFVNNLGTE---CAQELLVLTRNLL 173
                ||:|..|  |.|.:|.::..|:......|.  |::...:..:.|:   |.:|.|...::.:
Mosquito   206 ----IESKVFLLFQLLETLLRTGGREADIQHTLQQDHVWRLVIEGITTKDAVCRKETLATVQHAI 266

  Fly   174 ----QSDVRDDRRSAYF--LMHKLQEIDEVLAALQCSEVQWSAYVGIMENLEEQQSHLVLPTLST 232
                |.::  |....||  ...|..::...          |.::|.|:|.|.|.|:||:||.|.
Mosquito   267 GYAQQCEL--DLAGQYFNWSQDKSAQLTNA----------WQSFVTIVEALNESQTHLILPALE- 318

  Fly   233 LLPRMGLMSNNLSEDWLDWLRILCIRLLGDNNILVLRWTLKYFLSHFSLEQISRFNLLTQFLAAT 297
                   |...:....:.|..:|...:|...|..|:...|.|||.|.|.:. :...|..|||.|.
Mosquito   319 -------MIEKVQPLHVAWSNVLLRLILLHENGRVVNHGLNYFLQHRSFDP-TETELEKQFLEAF 375

  Fly   298 NRTQLYNPEVPDCLTKQQITDFSAQFPAE----ILLEALVCVPWHAVP------LIH---WLQAW 349
            ||..|...      .::.||..||.:...    .|::.|..:.|.:|.      :||   ...|.
Mosquito   376 NRAALLEN------VQEMITKLSAYYGKREAFAYLVQTLPEIEWKSVQYYCLVRVIHNGAGELAG 434

  Fly   350 ELKQLPVVSKEL--LFKLGARVRSLQNPVLRGEAINYVIFSL---------SATID--------- 394
            |.|:|...:..|  |........|::|..||     ||.|.|         ..|.|
Mosquito   435 ECKRLDQAATMLRSLTSCAKLCHSIKNVPLR-----YVTFVLLVKSVNHFSEPTTDPGLLLAVVA 494

  Fly   395 ---------SLSLGDY-----LLFMESLYNT-----------IDRYQSHSQLAQKI--RNCSNLE 432
                     |:||..:     ..|.:.:.:|           .|.:.....||.:|  ..|...|
Mosquito   495 EMEKLTPIFSISLQQFQSEAGWTFCDHIADTALMPLLEQVTVADTFFVEQVLASRIVEHGCIKNE 559

  Fly   433 KHI-----ASFNI--RCCELVSQMDY---------KHDVFVAFLEKLRTVPKSKHGWWRLLPIFL 481
            :.:     |:|.:  :..:|..::|:         .|....:..|..:|.....|..:.||....
Mosquito   560 QLLDVLIDANFPVCLKVFQLFPKLDHLLRQTISGIVHSTISSLKEGKKTNDPIPHKTFTLLAEMF 624

  Fly   482 H--------RELD--------HPEQYL----------------------------DFYRSVY--- 499
            |        .||:        |.|:.:                            |..|:||
Mosquito   625 HLNNAQALSTELESELNLLRLHLEEIVSERLQCFDYAQPSAKETIQLTHLIAAQGDLDRTVYPFF 689

  Fly   500 ------DLDTSF----LESGVSLEQMQQHLLN-RLDCQTRE---EKSFVLEHSVDLFVQINLPTW 550
                  :|:|||    .|...|::|:...:.. .|.|:.|.   .|.|..|           ..|
Mosquito   690 ASVSLKELETSFGRYQSEQPPSIDQLYVMIAEIYLHCRQRSPKCSKMFTSE-----------ACW 743

  Fly   551 SKLEVLNLNPLELLDRGTEETFATLSNILSTHDEQLA-----DQNVLPA---------------- 594
            |||       :.|||.|.......:.:||.|..|::.     ||.:||.
Mosquito   744 SKL-------INLLDVGNIHVLTVVIDILQTDGEKIGSDWYDDQALLPVVDRCYSEILNYRKSDH 801

  Fly   595 FISRLGKLKVRETQAILKYAVQNLSSEEYE-KCVV-----DVLEKNTFL--LGTMDCEEYIKAPT 651
            |:..:.|......|..:....:.:.|||.. .|.|     .:||:.:.:  |..:..|...:.|.
Mosquito   802 FMRLMEKFVRMLFQPYVACRPETIESEEITIACFVTGYVGKLLEQASTIGGLANVVYESMYRLPV 866

  Fly   652 SFVI------KRMLQ----GETTTGDARIER----------AFEQ-----ISDTGAMDRV--QFI 689
            ..::      |.:||    ||....:.::|.          .|:|     ::...|..||  ..:
Mosquito   867 ELLLDWLGFDKLLLQGIIFGEVPKREQKLESDVIDACGVPLPFKQHSRHHLAQADARVRVLCVLV 931

  Fly   690 QYAKNSTGLDISFICDDLLRMNN-------ELSRKKPRYFANCKEHRMKMRIGKAL---LDLSDR 744
            .|...||...::.:.  ||::..       :|::.|.||:|:...||.|:||.:||   |.|:..
Mosquito   932 LYRIASTNHPVAVLF--LLKVERMLIERFAQLTKTKERYYADSITHRQKLRIVQALCVVLKLTGT 994

  Fly   745 WKWSDNLWEAVLCPSDQPNISFMYEYLVSKMLPSIDLLLEQLKLLATLKPSQQISLVSVVHIYCL 809
            ..:.  :..|:|..::||||::::|.:|:      |..::.|.:.:||: ::|:.:..:..::.:
Mosquito   995 QPYP--VLNAMLYETNQPNINYLFELIVA------DSTIDTLTIWSTLR-NEQVKVSGIQSVFVI 1050

  Fly   810 TRWESIQHEQLVE--VFAVLLPLTMGANFQTRLLAQLVLHRICSEC--EDRSIQMPIADALKKSI 870
            . |.....||.::  ...:|||.||..||.|||.||:.:.::....  .:|.....|.||:...:
Mosquito  1051 L-WLRCCREQALDERYINLLLPWTMAQNFSTRLYAQITIKKLLERFAQHNRGPLRQIYDAVNSYL 1114

  Fly   871 KVTLSEKLTEFQC------------EARLLLPELGKQCPTSVSDCILMMTNAPFDENIS---FIS 920
            :....|:..| :|            ...|.|..:....| .|||       ||.::.:.   .:.
Mosquito  1115 RQGNVERNIE-RCMKDFRFGGVLDGHNLLTLANVFHNIP-KVSD-------APAEDVVGMDVLLE 1170

  Fly   921 C--SYD---FRMKLKRALETF---KRKQSVLIPELATSLAALNGNVQRKMNPVGDIYPESDFVV- 976
            |  ::|   ....|.:.||..   ..|:..|.  ||.|... :..||||:.|:..:.|..:.::
Mosquito  1171 CIQAHDGGCGEKNLGQVLEFHTLPAEKRETLF--LAQSFGG-SDFVQRKIVPLKSLEPNPELLLG 1232

  Fly   977 ------SNKARDDHELIVVASLIDKLPNLGGLARTCEVLGVNTLILGLKSQAEKSDFTNLSMTAE 1035
                  :.|......|||||||:::.|||||||||.|:..:..|::.........:|..||||||
Mosquito  1233 LPQHLCAKKMDCTDGLIVVASLVNRAPNLGGLARTGEIFAIKQLVINSLQDIGNKEFQALSMTAE 1297

  Fly  1036 KTLNILEVNPESLAGFLLEKQMEGYKIVGAEQTAHSTNFVDFKFPKKSILLLGHEKHGIPANLIG 1100
            |.|.|.|:....:..:|.|.:.:||.:||||||..|......:|||||:|:|||||:|:||.:|.
Mosquito  1298 KWLKIGELKTHRVVEYLREMKEKGYSVVGAEQTTGSKPIHQLQFPKKSVLVLGHEKNGLPAEIIR 1362

  Fly  1101 FLDYAVEIPQYGLVRSLNVHVAGSLFIWEYCKQH 1134
            .||...||||:|:||||||||.|::|:|||.|||
Mosquito  1363 HLDLIGEIPQFGVVRSLNVHVTGAIFMWEYAKQH 1396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18596	NP_651031.1	SpoU-like_TRM3-like	986..1130	CDD:349964	73/143 (51%)
LOC4576628	XP_001237715.3	None