Protein Alignment CG18596 and T14B4.1

DIOPT Version :10

• Sequence 1: NP_651031.1
• Gene: CG18596 / 42622
• FlyBaseID: FBgn0038953
• Length: 1136
• Species: Drosophila melanogaster
• Sequence 2: NP_495375.3
• Gene: T14B4.1 / 174110
• WormBaseID: WBGene00020498
• Length: 1225
• Species: Caenorhabditis elegans
• Alignment Length: 1307
• Identity: 281/1307 - (21%)
• Similarity: 481/1307 - (36%)
• Gaps: 386/1307 - (29%)

  Fly   121 EAKFVLQQLWSLSQSN-ERQPHAAQILVHL----FDDFVNNLGTECAQELLVLTRNLLQSDVRDD 180
            |::..::..|:....| :.....|..|.:|    .::|...|.|.|.         :...|:.|.
 Worm     5 ESEIQIRAYWNRRAENVDGDESVADFLAYLRIVDQNEFQIALPTLCI---------VAAKDITDS 60

  Fly   181 RRSAY--FLMHKLQEIDE-------VLAALQ--CSEVQWSAYVGIMENLEEQQSHLVLPTLSTLL 234
            |:..:  .....|.:.:.       |:|.|:  ||...|:.:..::|.|||.|.|::.|    :|
 Worm    61 RKKEFEGICADVLLDAESSRPSRRAVIACLKEFCSGSAWTDFYTLVEALEEPQFHIIRP----VL 121

  Fly   235 PRMGLMSNNLSEDWLD--WLRILCIRLLGDNNILVLRWTLKYFLS----------H--------- 278
            ||...:.|::.:..|:  ||::...|.:...|..:..|.::..:|          |
 Worm   122 PRFDTLLNSVRDGKLNFQWLKVALFRAMLHTNGWIRVWAIEKSISIDASILKDNDHVITSLIIPN 186

  Fly   279 ------------------FSLEQISRFNLLTQ---FLAATNRTQLYNPEVPDC------------ 310
                              |.::..|.||.:.:   |:    |..|.:.|:..|
 Worm   187 LNNNDVFWRNLEKGRMDAFLIQLGSMFNSIRETPDFI----RNLLVSIELMSCPTAIFFVVSALR 247

  Fly   311 -LTKQQITDFSAQFP--AEILLEALVCVPWHAVPLIHWLQAWELKQLPVVSKELLFKLGARVRSL 372
             :.|.:|.: |...|  ..::|:|      ..:|  |       |.:.:::...|....|::..|
 Worm   248 SIAKTEILN-SDDVPLLRRVVLKA------RYIP--H-------KSIRIITIRNLIVFYAKITRL 296

  Fly   373 QNPVLR--GEAINYVIFSLSAT---IDS--------LSLGDYL--------LFMESLYNTIDRYQ 416
            ...:|.  ...|:|:  |..||   ||:        |....|:        :|.::..|......
 Worm   297 DGTLLHELSNLISYI--SQDATSIMIDAVFKEIQNILDETSYIANENQDENVFHQTFGNDSKNLG 359

  Fly   417 SHSQL---------AQKIRNCSNLEKHIASF--NIRCCELVSQ----------MDYKHDVFVAFL 460
            .|:::         .||.|..|.|:..::..  .....:|.||          ||:..||.....
 Worm   360 LHAKMWWISMGKATIQKERMLSRLQLEVSELLGEKPTADLTSQLFLLKERPENMDFSSDVLECMK 424

  Fly   461 ----EKLRTVPKSKHGWWRLL--------PIFLHRELDH-------------------------- 487
                |.:.|...|..|..|.|        |:| ::...|
 Worm   425 NDLGEYILTQIISNKGSKRELELLQSLHIPLF-NKYCSHLSIPFALAVVQVLGDLKTCESATVCL 488

  Fly   488 ----------PEQ-----YLDFY---------------RSVYDLDT-SFLESGVSLEQMQQHLLN 521
                      ||:     .::||               :||.:.:| .|.:...:|..::..|||
 Worm   489 TFFNALVENVPEERYETLAIEFYKYLGGNEVIGMKRMKKSVEEYETKEFNQISATLHSLRLSLLN 553

  Fly   522 RLDCQTREEKSFVLEHSVDLFVQINLPTWSKLEVLNLNPLELLDRGTEETFA--TLSNILSTHDE 584
            :. .:..:|..|:.|....|.|....|...:|.:|   ....:.:.|:...|  .:....|..:|
 Worm   554 KF-IKDVDENQFLSECVEQLDVASAFPVKQQLCLL---IARFIKKCTDHKLALDCIRASASIVNE 614

  Fly   585 QLADQNVLPAFIS-------------RLGKLKVRETQAILKYAVQNLSSEEYEKCVVDVLEKNTF 636
            :....|.|||..|             .:.:..:...:|.|..|.|   |......:||.:.|...
 Worm   615 EKKSLNSLPALRSFFHVALSGPQSDPVIAQESIELLEAQLAVASQ---STPIALILVDAITKYQT 676

  Fly   637 LLGTMDCEEYIKAPTSFVIKRMLQGETTTGDARI-----ERAFEQISDTGAMDRV----QFIQYA 692
            .|      :...||  |::|..|.|.....::|:     ...||:.......|:|    :.:|.|
 Worm   677 NL------DVNWAP--FIVKLALFGPVPKKESRVISYAYSMIFEEEGSYLKKDQVERLDEVVQTA 733

  Fly   693 ---------KNSTGLD-----ISFICDDLLRMNNELSRKKPRYFANCKEHRMKMRIGKAL----L 739
                     |.||.:|     |:.| :::.:.:..:.:...|.|.....||.|.|..:.|    |
 Worm   734 RFKAVLLALKLSTVVDGNAWRIALI-EEIFKASAIMDQSSSRSFGLSMAHRQKTRAVELLHLLAL 797

  Fly   740 DLSDRWKWS---DNLWEAVLCPSDQPNISFMYEYLVSKMLPSIDLLLEQL------KLLATLKPS 795
            .:.|:...|   |.....|:.|..|.:|..:.|:.::.:....:.|.|:|      |.:|:.:..
 Worm   798 KIEDQESASKVFDFCINCVVDPCQQFSIKLIVEWTLAMLCVKFEKLFEKLIDEEFEKNMASQRIG 862

  Fly   796 QQISLVSVVHIY----------CLTR---WESIQHEQLVEVFAVLLPLTMGANFQTRLLAQLVLH 847
            ...|.::|:::.          ||.:   |.:.|                  ||..|..| |...
 Worm   863 SICSWLNVLNLIARVAPKFVDSCLDKVIVWCTAQ------------------NFPVRCTA-LAAA 908

  Fly   848 RICSECEDRSIQMPIADALKK--SIKVTL---------SEKLTEFQCE----ARL---------- 887
            |:.....|:       |..||  .:|..:         |:::.:..|.    |:|
 Worm   909 RLMFSTFDK-------DRRKKWRIVKAIVNFDAEPSGNSKRVIDNLCSDFYFAKLHINDHFNFQT 966

  Fly   888 LLPELGKQC-----PTSVSDCILMMTN-----APFDENISFISCSYDFRMKLKRALETFKRKQSV 942
            :|.|:.|:.     .|..::.|:.|.|     ...:|:..|:|...:....|.        |.:.
 Worm   967 ILSEIAKRTGMPPEETIPNNIIMEMNNITHQIKSMNEDQEFLSAPSEVYSALS--------KNAS 1023

  Fly   943 LIPELATSLAALNGNVQRKMNPVG-DIYPES---------DFVVSNKARDDH-ELIVVASLIDKL 996
            ..|.:.      |.:|..:.:|:. |..||:         ..|..|:..|.. .|||||||:||.
 Worm  1024 CAPSME------NEDVGEEESPIEFDEQPENTNASTSFQRKIVKENELNDGGISLIVVASLVDKP 1082

  Fly   997 PNLGGLARTCEVLGVNTLILGLKSQAEKSDFTNLSMTAEKTLNILEVNPESLAGFLLEKQMEGYK 1061
            .||||:.||.|:.||:||::.....|:.::|..|||::|....|..|...:|..:|...:..||.
 Worm  1083 NNLGGICRTSEIFGVDTLVVADVLVAQDANFKALSMSSENWQKIEGVKRTNLLPYLQNLRANGYT 1147

  Fly  1062 IVGAEQTAHSTNFVDFKFPKKSILLLGHEKHGIPANLIGFLDYAVEIPQYGLVRSLNVHVAGSLF 1126
            ::.||||..|....||.||||:::::|.||.|:|.||:..:|..|||.|.|..|||||||..:|.
 Worm  1148 VIAAEQTTDSVMMHDFVFPKKAVIVMGDEKEGVPVNLLRAVDQTVEIKQVGHTRSLNVHVTAALM 1212

  Fly  1127 IWEYCKQ 1133
            |.::.:|
 Worm  1213 IAKFAEQ 1219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18596	NP_651031.1	SpoU-like_TRM3-like	986..1130	CDD:349964	65/143 (45%)
T14B4.1	NP_495375.3	SpoU-like_TRM3-like	1072..1216	CDD:349964	65/143 (45%)