Protein Alignment CG6015 and cdc40

DIOPT Version :10

• Sequence 1: NP_651005.1
• Gene: CG6015 / 42593
• FlyBaseID: FBgn0038927
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001011457.1
• Gene: cdc40 / 496947
• XenbaseID: XB-GENE-954563
• Length: 567
• Species: Xenopus tropicalis
• Alignment Length: 577
• Identity: 350/577 - (60%)
• Similarity: 432/577 - (74%)
• Gaps: 14/577 - (2%)

  Fly     1 MLGLQSYASSSDEESDHADAATATTNSEPSAPIPDHLLPVDKTHSLSKSIAVCAAPTVVPLGASA 65
            :..|.||.|:||.:|: ||:...:.:.:...|....|..||            :||.|.......
 Frog     4 LTSLVSYGSASDSDSE-ADSEDCSAHLKSLPPGTGVLRVVD------------SAPEVAVKEDVE 55

  Fly    66 VPRTLDPTLKEVTYNPRYEEMYAPVKGPEHPDLTMQQRAPRNTLAGYVEKAHINAFEFENQRRTF 130
            ....|||..|||.:||.||.|:||..||::|..|.|..||||.|:||.|..|||.|.||.|||||
 Frog    56 TGDHLDPYAKEVQFNPTYETMFAPEFGPKNPFKTQQMAAPRNMLSGYAEPTHINDFMFEQQRRTF 120

  Fly   131 HTYGYALDPSVDDQADGQSFVGDLQSAYDDNGKTVFEPPKAKK-LRKQEKNDNPEDIEGFLGPWG 194
            .|||||||||:|.|.....::|.:..|..:.|.||||..:.|. .||:.|..:..:|:||||||.
 Frog   121 ATYGYALDPSIDHQETSTKYIGSVDEAEKNQGLTVFETTQKKSDKRKKVKGSDASNIDGFLGPWA 185

  Fly   195 KFENEVSVAKPNEQERAELDELLSKRHKRGRIPEDKPLEEKSTLHIKDAYDYQGRSYLHAPHDLG 259
            |:.:|..||||:|:|:.||||:.:||.|||:..||||.|||:.||:|:.||||||||||.|.|:.
 Frog   186 KYIDEKDVAKPSEEEQKELDEITAKRQKRGKQEEDKPAEEKTILHVKEMYDYQGRSYLHIPQDID 250

  Fly   260 VNLRSNAPPTKCFLPKAHIHTWSGHNKGISSIRWFPKTAHLLLSGSMDCRVKLWEVYGERRCIRT 324
            |||||...|.||:|||..||.||||.||:|::|.||.:.|||||.||||::||||||.:|||:||
 Frog   251 VNLRSTEFPEKCYLPKKQIHVWSGHTKGVSAVRLFPVSGHLLLSCSMDCKIKLWEVYKDRRCLRT 315

  Fly   325 FSGHRQAIKDIAWNNRGTNFLSASYDRYIKLWDAETGDVVSRFTTRKMPFCVKFHPDNSKQHLFV 389
            |.||.:|::||::||.||.||||:||||:||||.|||..:||||.||:|:||||:||..||.|||
 Frog   316 FIGHSKAVRDISFNNAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQSLFV 380

  Fly   390 AGTSDKKIICWDTRSGDIVQEYDRHLGSVSTITFVDDNRRFVTTSDDKSMRIWEWDIPVDMKYIA 454
            ||.|||||:.||.|||:||||||||||:|:||||||:|||||:||||||:|:||||||||.||||
 Frog   381 AGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTITFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIA 445

  Fly   455 DPTMHSMPAVTLAPNGKWMACQSLDNKIVIFSALNRFKMNRKKTFTGHMVSGYACQLDFSPDMSY 519
            :|:|||||||||:|||||:||||:||:|:||.|.|||::|:||.|.||||:|||||:||||||||
 Frog   446 EPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSY 510

  Fly   520 LVSGDGDGKCYIWDWKTTKMYKKWQAHDGVCISALWHPHEASKVVTAGWDGQIKYWD 576
            :||||.|||..||||||||:|.:.:|||.|||||:|||||.|||:|.||||.||.||
 Frog   511 VVSGDADGKLNIWDWKTTKLYSRLKAHDKVCISAVWHPHETSKVITCGWDGLIKLWD 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6015	NP_651005.1	WD40	277..576	CDD:238121	216/298 (72%)
		WD40 repeat	289..327	CDD:293791	25/37 (68%)
		WD40 repeat	332..368	CDD:293791	23/35 (66%)
		WD40 repeat	374..412	CDD:293791	27/37 (73%)
		WD40 repeat	418..453	CDD:293791	28/34 (82%)
		WD40 repeat	461..500	CDD:293791	27/38 (71%)
		WD40 repeat	509..532	CDD:293791	17/22 (77%)
cdc40	NP_001011457.1	WD40	269..567	CDD:238121	216/297 (73%)
		WD40 repeat	280..318	CDD:293791	25/37 (68%)
		WD40 repeat	323..359	CDD:293791	23/35 (66%)
		WD40 repeat	365..403	CDD:293791	27/37 (73%)
		WD40 repeat	409..491	CDD:293791	62/81 (77%)
		WD40 repeat	499..535	CDD:293791	27/35 (77%)
		WD40 repeat	541..566	CDD:293791	19/24 (79%)