Protein Alignment CG6015 and Wdr25

DIOPT Version :10

• Sequence 1: NP_651005.1
• Gene: CG6015 / 42593
• FlyBaseID: FBgn0038927
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_808270.2
• Gene: Wdr25 / 212198
• MGIID: 3045255
• Length: 535
• Species: Mus musculus
• Alignment Length: 515
• Identity: 137/515 - (26%)
• Similarity: 213/515 - (41%)
• Gaps: 108/515 - (20%)

  Fly    89 PVKGPEHPDLTMQQRAPRNTLAGYVEKAHI------NAFEFENQRRTFHTYGYALDPSVDDQADG 147
            |...|..|.|.| .|||    .|:|..|..      .|::             .|.|| .||:..
Mouse   100 PPSEPPRPSLWM-SRAP----VGHVPLAAACLKPLKPAWD-------------VLKPS-HDQSTF 145

  Fly   148 QSFVGDLQSAYDDNGKTVFEPPKAKKLRKQEKNDNPEDIEGFLG-----PWGKFENEVSVAKPNE 207
            :|..|:..|:....|:....|...|:|| |.:..|||...|..|     |.|.....:.|| |..
Mouse   146 ESTAGNASSSQRKRGEDCVLPYIPKRLR-QLQALNPEAGGGKDGEPPGPPAGCAPAPLCVA-PTV 208

  Fly   208 QERAELDELLSKRHKRGRIPEDKPLEEKSTLHIKDAYDYQGRSYLHAPHDLGVNLRSNAPPTKCF 272
            .|  .:...|:.:::...:|      :|...|::
Mouse   209 SE--FIQPYLNSQYRETTVP------KKVLFHLR------------------------------- 234

  Fly   273 LPKAHIHTWSGHNKGISSIRWFPK--TAHLLLSGSMDCRVKLWEVYGERRCIRTFSGHRQAIKDI 335
                      ||...::||:|.|.  .:|:|||.|||...|:|.......|::|:|.|.:|::..
Mouse   235 ----------GHRGPVNSIQWCPVFCKSHMLLSASMDKTFKVWNAVDSGHCLQTYSVHSEAVRAA 289

  Fly   336 AWNNRGTNFLSASYDRYIKLWDAETGDVV------SRFTTRKMPFCVKFHPDNSKQH-LFVAGTS 393
            .|:..|...||..:|..:.|.|.|||..|      .|.||      :||||   |.| :|:.|..
Mouse   290 RWSPCGRRILSGGFDFALHLTDLETGTQVFSGQSDFRVTT------LKFHP---KDHNVFLCGGF 345

  Fly   394 DKKIICWDTRSGDIVQEYDRHLGSVSTITFVDDNRRFVTTSD----DKSMR-IWEWDIPVDMKYI 453
            ..:|..||.|:|.:|:.|...:.....|.|:.:...|::::|    |.:.| |..||.....| |
Mouse   346 SSEIKAWDMRTGKVVKGYKATIQQTLDILFLQEGSEFLSSTDASTRDSADRTIIAWDFRTAAK-I 409

  Fly   454 ADPTMH---SMPAVTLAPNGKWMACQSLDNKIVIFSALNRFKMNRKKTFTGHMVSGYACQLDFSP 515
            ::...|   :.|::.|.|.......|:..|.:.:||::..::|:|::.:.||.|.|||...:.||
Mouse   410 SNQIFHERYTCPSLALHPREPVFLAQTNGNYLALFSSVWPYRMSRRRRYEGHKVEGYAVGCECSP 474

  Fly   516 DMSYLVSGDGDGKCYIWDWKTTKMYKKWQAHDGVCISALWHPHEASKVVTAGWDGQIKYW 575
            ....||:|..||:..::.::|.......|.|...|:...:||...|.:.|..|.|.||.|
Mouse   475 CGDLLVTGSADGRVLMFSFRTASRACTLQGHTQACLGTTYHPVLPSVLGTCSWGGDIKIW 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6015	NP_651005.1	WD40	277..576	CDD:238121	96/316 (30%)
		WD40 repeat	289..327	CDD:293791	15/39 (38%)
		WD40 repeat	332..368	CDD:293791	12/41 (29%)
		WD40 repeat	374..412	CDD:293791	14/38 (37%)
		WD40 repeat	418..453	CDD:293791	10/39 (26%)
		WD40 repeat	461..500	CDD:293791	9/38 (24%)
		WD40 repeat	509..532	CDD:293791	7/22 (32%)
Wdr25	NP_808270.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..108		2/7 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	141..160		5/18 (28%)
		WD40	230..534	CDD:238121	96/354 (27%)
		WD 1	235..277		16/41 (39%)
		WD40 repeat	242..281	CDD:293791	15/38 (39%)
		WD 2	281..320		13/38 (34%)
		WD40 repeat	287..321	CDD:293791	11/33 (33%)
		WD 3	321..362		17/49 (35%)
		WD40 repeat	327..364	CDD:293791	16/45 (36%)
		WD 4	365..411		11/46 (24%)
		WD40 repeat	371..413	CDD:293791	11/42 (26%)
		WD 5	415..454		9/38 (24%)
		WD40 repeat	420..459	CDD:293791	9/38 (24%)
		WD 6	460..501		14/40 (35%)
		WD40 repeat	467..503	CDD:293791	9/35 (26%)
		WD 7	504..535		11/31 (35%)
		WD40 repeat	509..534	CDD:293791	9/24 (38%)