Protein Alignment: Qsox2 and QSOX1

• Sequence 1: NP_650998.1
• Gene: Qsox2
• FlyBaseID: FBgn0038919
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_002817.2
• Gene: QSOX1
• HGNCID: 9756
• Length: 747
• Species: Homo sapiens
• Alignment Length: 572
• Identity: 176/573 (31%)
• Similarity: 286/573 (50%)
• Gaps: 81/573 (14%)

  Fly     5 LKTLLYCLLLISPADVLGRLNARKSANEASLYSDTDNVIMLDIESLRPA-LNLKNSKLVQFLNSF 68
            |..||..||.:..|:         :|..::|||.:|.:.:|..:::|.| |..:::..|:|..|:
Human    14 LLLLLLWLLAVPGAN---------AAPRSALYSPSDPLTLLQADTVRGAVLGSRSAWAVEFFASW 69

  Fly    69 CGDCHRFAPVFKTLSRDLYKWRRILRIYAVDCAQERNAQLCREFNIRQTPSLRFFGPDMRKNDDV 133
            ||.|..|||.:|.|:.|:..||..|.:.|:|||:|.|:.:||:|||...|::||| ....||..
Human    70 CGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPTVRFF-KAFTKNGS- 132

  Fly   134 LGAVIP--GQDPEFISSTLAE-LVSQND-YGPGQPNFRPLKATDYEIFQDQDGETPIQFVALVLQ 194
             |||.|  |.|.:.:...|.: |.|.:| :.|..|...|.|..:.:.|..::.|   :::||:.:
Human   133 -GAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFFARNNE---EYLALIFE 193

  Fly   195 PKNSKIGRDTLLELLPFKELSVRII--EDSQIFNEFGLGPDDQKLAIVDRNG------------- 244
            ...|.:||:..|:|...|.::||.:  .::.:..:||: .|.....::.|||
Human   194 KGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGV-TDFPSCYLLFRNGSVSRVPVLMESRS 257

  Fly   245 --TAQYLTPSSDSSEAYASTIGDFLKNRNIQPDPPLPIAVAPNFTEFLDHQNQAILTKVLTPPLQ 307
              ||.....|..:.||..:|:.....|:           :||...:..|..             :
Human   258 FYTAYLQRLSGLTREAAQTTVAPTTANK-----------IAPTVWKLADRS-------------K 298

  Fly   308 VYRADLEQAIDKLLHIELRKWVLLEGNSLNALKNIIKIFRYLNPLNKDGKLLLTDLDNSLS---- 368
            :|.||||.|:..:|.||:.::.:|||..|.|||..:.:.....|    |:.|:.:..:|::
Human   299 IYMADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFP----GRPLVQNFLHSVNEWLK 359

  Fly   369 --SKQSIKGADFGDLVDSLENGRRVFKARRYVGCIGSRPLLRSFTCSMWTLFHHLTVEAAK---- 427
              .:..|..:.|...:|..:.|..:.|...::||.||.|..|.|.||:|.|||.|||:||:
Human   360 RQKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAARQNVD 424

  Fly   428 -PPNYFEAGSILKTFHGFAKYFFGCTDCSEHFQQMAIRRNLTSVKTHDEEILWLWAAHNEVNARI 491
             .....:|..:|....|:..|||||.||:.||:||| ..::..|.:.:..:||||::||.||||:
Human   425 HSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMA-AASMHRVGSPNAAVLWLWSSHNRVNARL 488

  Fly   492 AGDSTEDPKFPKIQFPSAENCPTCRSNDSE---WRTDEVLKYLKQLYDINNV 540
            ||..:|||:|||:|:|..|.|..|.:...:   |..:..|.:||..:..:|:
Human   489 AGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNI 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Qsox2	NP_650998.1	PDI_a_QSOX	40..152	CDD:239290	44/115 (38%)
		Evr1_Alr	413..504	CDD:282612	44/96 (46%)
QSOX1	NP_002817.2	PDI_a_QSOX	40..152	CDD:239290	44/115 (38%)
		Evr1_Alr	406..501	CDD:282612	44/96 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C2389635
eggNOG	1	0.900				E1_KOG1731
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	264	1.000	Inparanoid score	I3024
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	1	1.010				D158783at33208
OrthoFinder	1	1.000				FOG0001145
OrthoInspector	1	1.000				T130188
orthoMCL	1	0.900				OOG5_129038
Panther	1	1.100			O	PTHR22897
Phylome	1	0.910		0.800	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R3816
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	13	12.800