DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6800 and CG7236

DIOPT Version :9

Sequence 1:	NP_650984.1	Gene:	CG6800 / 42562	FlyBaseID:	FBgn0038902	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_608950.3	Gene:	CG7236 / 33798	FlyBaseID:	FBgn0031730	Length:	438	Species:	Drosophila melanogaster

Alignment Length:	234	Identity:	85/234 - (36%)
Similarity:	133/234 - (56%)	Gaps:	11/234 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YAP------SRYKMLEKIGEGVHGCVFKAIDLQRNKEVAIKKVALKNKFGNIALNTLREIKTLQL 62
            |.|      .||:.|.::|||.:|.|:|..|.:....||:|:.........|....||||:.|:.
  Fly    39 YRPQGSSKMDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKN 103

  Fly    63 CKSEYILDIIDIYPDLTGLSLVLEYQPDTLYNRLKSEVNPLSRQQVRKFAHQMFKGIAYLHEAGL 127
            .|...::.:::::.....|.||.|:...|:.:.|:...........::..:|...|:||.|:.|.
  Fly   104 LKHPNLVSLLEVFRRKRRLHLVFEFCELTVLHELERHPQGCPEHLTKQICYQTLLGVAYCHKQGC 168

  Fly   128 MHRDIKPANLLISDTDMLKIADFGLARLYFPEDESRLYSPQVSTRWYRAPEILFGSQKYGTGVDM 192
            :||||||.|:|::....:|:.|||.||:..|.:.   |:..|:||||||||:|.|..:|||.||:
  Fly   169 LHRDIKPENILLTAQGQVKLCDFGFARMLSPGEN---YTDYVATRWYRAPELLVGDTQYGTPVDV 230

  Fly   193 WAAGCVVAEMLRGVPLFAGTTDIEQLAIIIRTLGS--PR 229
            ||.||:.||::||..|:.|.:|::||.:|.:|||.  ||
  Fly   231 WAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPR 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6800	NP_650984.1	STKc_CCRK	8..295	CDD:270826	83/224 (37%)
CG6800	NP_650984.1	S_TKc	9..288	CDD:214567	82/223 (37%)
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	83/225 (37%)
CG7236	NP_608950.3	Pkinase	50..335	CDD:278497	82/223 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442468
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940