Protein Alignment E2f1 and E2f6

DIOPT Version :10

• Sequence 1: NP_001262809.1
• Gene: E2f1 / 42550
• FlyBaseID: FBgn0011766
• Length: 821
• Species: Drosophila melanogaster
• Sequence 2: NP_001094187.1
• Gene: E2f6 / 313978
• RGDID: 631412
• Length: 272
• Species: Rattus norvegicus
• Alignment Length: 214
• Identity: 75/214 - (35%)
• Similarity: 122/214 - (57%)
• Gaps: 30/214 - (14%)

  Fly   252 RNRADTSLGILTKKFVDLLQESPDGVVDLNEASNRLHVQKRRIYDITNVLEGINILEKKSKNNIQ 316
            |.|.|.||..||:||:||::.:|.|::|||:.:.:|.|:|||:|||||||:||.::||||||:|:
  Rat    61 RPRFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIELVEKKSKNHIR 125

  Fly   317 WRCGQSM---VSQERSRHIEADSLRLEQQENELNKAIDLMRENLAEISQEVENSGGMAYVTQNDL 378
            | .|..:   .:..:.:.::|:...|...|:.|::.|....:.|.|::.:.||. .:||||..|:
  Rat   126 W-IGSDLNNFGAAPQQKKLQAELSDLSAMEDALDELIKDCAQQLLELTDDKENE-RLAYVTYQDI 188

  Fly   379 LNVDLFKDQIVIVIKAPPEAKLVRSATALKFQPLPFNLNLPNTKLPRE----IYVKAENSGEINV 439
            ..:..|.:||||.:|||.|.:|                   :...|||    ::::: ..|.|:|
  Rat   189 HGIQAFHEQIVIAVKAPEETRL-------------------DVPAPREDSITVHIRS-TKGPIDV 233

  Fly   440 FLCH-DTSPENSPIAPGAG 457
            :||. :.:..|...|.|.|
  Rat   234 YLCEVEQNHSNGKTADGVG 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E2f1	NP_001262809.1	E2F_TDP	256..318	CDD:460530	35/61 (57%)
		E2F_DD	327..444	CDD:473951	32/121 (26%)
		coiled coil	327..362	CDD:271137	7/34 (21%)
E2f6	NP_001094187.1	E2F_TDP	64..128	CDD:460530	36/64 (56%)
		E2F_DD	139..239	CDD:271137	32/120 (27%)
		coiled coil	139..173	CDD:271137	7/33 (21%)