Protein Alignment E2f1 and E2f3

DIOPT Version :10

• Sequence 1: NP_001262809.1
• Gene: E2f1 / 42550
• FlyBaseID: FBgn0011766
• Length: 821
• Species: Drosophila melanogaster
• Sequence 2: XP_011242577.1
• Gene: E2f3 / 13557
• MGIID: 1096340
• Length: 467
• Species: Mus musculus
• Alignment Length: 299
• Identity: 103/299 - (34%)
• Similarity: 162/299 - (54%)
• Gaps: 52/299 - (17%)

  Fly   226 SHHPF---SLSTPQQQLAASVAS------SSSSGDRNRADTSLGILTKKFVDLLQESPDGVVDLN 281
            |.|.:   .|.||:.:..|::.|      ..|..::.|.|||||:|||||:.||.:|||||:|||
Mouse   143 SGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLN 207

  Fly   282 EASNRLHVQKRRIYDITNVLEGINILEKKSKNNIQWR-CGQS----MVSQERSRHIEADSLRLEQ 341
            :|:..|.||||||||||||||||::::||||||:||. |..|    |::|  .:.:..:...|.|
Mouse   208 KAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQ--CQGLSKEVTELSQ 270

  Fly   342 QENELNKAIDLMRENLAEISQEVENSGGMAYVTQNDLLNVDLFKDQIVIVIKAPPEAKLVRSATA 406
            :|.:|::.|.....:|..::::.||. .:||||..|:..:...|||.|||:|||||.:
Mouse   271 EEKKLDELIQSCTLDLKLLTEDSENQ-RLAYVTYQDIRKISGLKDQTVIVVKAPPETR------- 327

  Fly   407 LKFQPLPFNLNLPNTKLPREIYVKAENSGEINVFLCHDTSPENSPI------------APGAGYV 459
                     |.:|::....:|:: |...|.|.|:||.:.:..:.|:            .|.:..:
Mouse   328 ---------LEVPDSIESLQIHL-ASTQGPIEVYLCPEETETHRPMKTNNQDHNGNIPKPTSKDL 382

  Fly   460 GAPGAGCVRTATST-RLHPLTN-----QRLNDPLFNNID 492
            .:..:|....:.|| .|.||.:     |:..|.:.:|::
Mouse   383 ASNNSGHSDCSVSTANLSPLASPANLLQQTEDQIPSNLE 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E2f1	NP_001262809.1	E2F_TDP	256..318	CDD:460530	45/61 (74%)
		E2F_DD	327..444	CDD:473951	33/116 (28%)
		coiled coil	327..362	CDD:271137	6/34 (18%)
E2f3	XP_011242577.1	E2F_TDP	181..245	CDD:460530	46/63 (73%)
		E2F_DD	256..356	CDD:271137	34/119 (29%)
		coiled coil	256..291	CDD:271137	7/36 (19%)