Protein Alignment E2f1 and e2f7

DIOPT Version :10

• Sequence 1: NP_001262809.1
• Gene: E2f1 / 42550
• FlyBaseID: FBgn0011766
• Length: 821
• Species: Drosophila melanogaster
• Sequence 2: XP_002935684.2
• Gene: e2f7 / 100485885
• XenbaseID: XB-GENE-1018445
• Length: 872
• Species: Xenopus tropicalis
• Alignment Length: 799
• Identity: 162/799 - (20%)
• Similarity: 255/799 - (31%)
• Gaps: 268/799 - (33%)

  Fly   158 KVKRRPHAVSDEIHPKKQAKQSAHHQTVYQKHTASSAPQQLRHSHHQLRHDADAELDEDVVERVA 222
            ||..||.|  |...|           |...|...|:|..::|              |.:..:.:.
 Frog    73 KVAERPQA--DPWTP-----------TANLKMLISAASPEIR--------------DREKKKELF 110

  Fly   223 KPASHHPFSLSTPQQQLAASVASSSSSGDR-NRADTSLGILTKKFVDLLQESPDG----VVDLNE 282
            :|..::....:....||..||........| :|...|||:|.:||:......|..    .:.|:|
 Frog   111 RPIENNGIEETDTDLQLMDSVDDIDDLEKRPSRKQKSLGLLCQKFLARYPSYPISTEKMTISLDE 175

  Fly   283 ASNRLHVQKRRIYDITNVLEGINILEKKSKNNIQWRCGQSMVS---------------------- 325
            |::.|.|::||||||.||||.::::.:.:||...|. ||..::
 Frog   176 AASSLGVERRRIYDIVNVLESLHLVSRVAKNQYCWH-GQHNLNETLRNLQHIGEKQNYRAQIACF 239

  Fly   326 -------------QERSRHI-----------EAD------------SLRLEQQENEL------NK 348
                         ||:..||           |||            |||:..|:..:      .|
 Frog   240 NLRDMGMEYKCDEQEKGCHIDHLNTPLIELSEADCPSVSSSSRKDKSLRIMSQKFVMLFLVSTTK 304

  Fly   349 AI--DLMRENLAEISQEVENSGGM------AYVTQNDLLNVDLFK-------------------- 385
            .|  ::..:.|.|.||:..:....      .|...|.|.::.|.|
 Frog   305 IITLEIAAKILIEESQDAADHSKFKTKVRRLYDIANVLTSLGLIKKVHVTDERGRKPAFKWIGPV 369

  Fly   386 -----DQ---IVIVIKAPPEAK-----------------------LVRSATALKFQPL--PFNLN 417
                 ||   :...|.:|...|                       :|:|.:|:|.:..  |.:..
 Frog   370 DFTAEDQKMEVTTTIPSPDSKKDACNLSPASDRVKQRLFRHSSFNIVQSFSAVKRKVCSHPCSPQ 434

  Fly   418 LPNTKLPREIYV------------KAENSGEINVFLCHDTSPENSPIAPGAGYVGAPGAGCVRTA 470
            .|......:.|.            |||...:.......:.:.|||.: |.:..|..|.....|..
 Frog   435 KPQGVESSDSYASKMAHLATICKPKAEEDSKQISSTSRNGNIENSSL-PFSVVVPMPVDSDYRVK 498

  Fly   471 TSTRLHPLTNQR-------LNDPLFNNIDAMSTKGLFQTPY---------RSARNLS--KSIEEA 517
            ......||.:.:       :..|..:|.|..:...:...||         ....|||  |:.:..
 Frog   499 PVVHQVPLVSHKTVCEPLGIMPPSQSNEDCTNHGFVPNQPYMYLPSNSVFMLCGNLSEGKATDHL 563

  Fly   518 AKQSQPEYNNICDIAMGQHHNLNQQQQQQQQQLLQQPEEDDVDVELNQLVP---------TLTNP 573
            |....|...:  |....:...:::|::..::||     .|..|..|:.::|         :|..|
 Frog   564 AMSLYPVPGS--DSPTLEETTMSKQERPTKRQL-----NDKDDAPLSLVLPKKSRVDNTQSLQKP 621

  Fly   574 VVRTHQFQQHQQPSIQELFSSLTESSPPTPTKRRREAAAAAIAAGSS------------------ 620
            :.:|...:|.|..|.:|.::  ||     |..:...........||.
 Frog   622 ICKTTTPEQLQHVSREEEYN--TE-----PVTKHSNVGETTEEVGSRILPHENVHLHPAVPPQFL 679

  Fly   621 -TTATTTLNSHNNRNHSNHSNHSNHSSSNNSKSQPPTIGYGSSQRRS-DVPMYNCAMEGATTTSA 683
             ...|..|||.|....:|||                 .|...||..| :||.  ..:..:..|:.
 Frog   680 YVPTTQGLNSFNFLLPANHS-----------------AGLSQSQLASLNVPY--VMVPSSALTAF 725

  Fly   684 TADTTAATSRSAAASSL--QMQFAAVAESNNGSSSGGGGGGGGYGSIAGAGANADPHQP---YSH 743
            ....:.|.|..|:.|:|  :|.|     |..|:||       ....|.||...|.|..|   ...
 Frog   726 PFICSPAVSSGASGSTLNGRMNF-----SQAGTSS-------PTRLIIGAPQMAVPQPPEPAVDQ 778

  Fly   744 DRNSLPPGVADCDANSNSS 762
            .:|..|..|:...|...||
 Frog   779 TKNLSPLSVSPVSAKCASS 797

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E2f1	NP_001262809.1	E2F_TDP	256..318	CDD:460530	24/65 (37%)
		E2F_DD	327..444	CDD:473951	36/218 (17%)
		coiled coil	327..362	CDD:271137	14/65 (22%)
e2f7	XP_002935684.2	E2F_TDP	144..212	CDD:460530	25/68 (37%)
		E2F_TDP	283..367	CDD:460530	15/83 (18%)