DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bap and HOXD8

DIOPT Version :9

Sequence 1:	NP_732637.1	Gene:	bap / 42537	FlyBaseID:	FBgn0004862	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_062458.1	Gene:	HOXD8 / 3234	HGNCID:	5139	Length:	290	Species:	Homo sapiens

Alignment Length:	149	Identity:	47/149 - (31%)
Similarity:	68/149 - (45%)	Gaps:	23/149 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 DYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPP---LSSSPSE-----SPLSHDGSGLSRKKR 177
            |.:||:..:.....|..:....|.|:..:....|.   .|||||:     .|.:..|     ::|
Human   140 DNLQRQPIFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAAPG-----RRR 199

  Fly   178 SRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEAAL 242
            .|..:|..|..|||:.|....||:...|.|::.:|.|||.||||||||||.|.|::..:.
Human   200 GRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKD----- 259

  Fly   243 LGASKRVPVQVLVREDGST 261
                 :.||.....:||.|
Human   260 -----KFPVSRQEVKDGET 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeobox	178..231	CDD:278475	26/52 (50%)
HOXD8	NP_062458.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	60..127
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..200		10/43 (23%)
		Homeobox	201..253	CDD:278475	26/51 (51%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	255..290		5/29 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910