Protein Alignment bap and HOXD3

DIOPT Version :10

• Sequence 1: NP_732637.1
• Gene: bap / 42537
• FlyBaseID: FBgn0004862
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_008829.3
• Gene: HOXD3 / 3232
• HGNCID: 5137
• Length: 432
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 79/278 - (28%)
• Similarity: 108/278 - (38%)
• Gaps: 42/278 - (15%)

  Fly   115 SNSSAADYMQRKLAYFGSTLAAPLDMRRCTSNDSDC-DSPPPLSSSPSESPLSHDGSGLSRKKRS 178
            ::||:|...::...:...:.........|.:....| |..||       .|.|         ||.
Human   149 ASSSSATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPP-------GPAS---------KRV 197

  Fly   179 RAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQ---HEA 240
            |.|::.||:.|||:.|...|||..|.|.|||..|.|||.|:||||||||.|.|:.|..:   |..
Human   198 RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSP 262

  Fly   241 ALLGASKRVPVQVLVREDGSTTYAHMAAPGAGHGLD----PALINIYRHQLQLAYGGLP----LP 297
            |.....:..|   |....|...|:....|..|...|    ||......:...||....|    ||
Human   263 ASQSPERSPP---LGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNMYGLAAYTAPLSSCLP 324

  Fly   298 QMQMPFPYFYPQHKVPQPIPPPTQSSSFVTASSASSSPVPIPIPGAVRPQRTPCPSP--NGQMMS 360
            |.:.   |..|:.   :|.|..:....|.:|:...|   |:.:.|.......|...|  |...:|
Human   325 QQKR---YAAPEF---EPHPMASNGGGFASANLQGS---PVYVGGNFVESMAPASGPVFNLGHLS 380

  Fly   361 VESGAESVHSAAEDVDEN 378
            ..|.|...:|.|..:..|
Human   381 HPSSASVDYSCAAQIPGN 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeodomain	176..232	CDD:459649	32/55 (58%)
HOXD3	NP_008829.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..62
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..197		11/63 (17%)
		Antp-type hexapeptide	160..165		0/4 (0%)
		Homeodomain	195..251	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	253..280		6/29 (21%)
		DUF4074	369..430	CDD:463833	8/30 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	400..432