Protein Alignment bap and Nkx2-5

DIOPT Version :10

• Sequence 1: NP_732637.1
• Gene: bap / 42537
• FlyBaseID: FBgn0004862
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_032726.1
• Gene: Nkx2-5 / 18091
• MGIID: 97350
• Length: 318
• Species: Mus musculus
• Alignment Length: 389
• Identity: 119/389 - (30%)
• Similarity: 155/389 - (39%)
• Gaps: 115/389 - (29%)

  Fly    17 SKSLT-TPFSINDILTRSNPETRRMSSVDSEPEPE-KLKPSS----------------------- 56
            |.:|| ||||:.|||.... :.|.::|.|.....| .|.|:|
Mouse     4 SPALTPTPFSVKDILNLEQ-QQRSLASGDLSARLEATLAPASCMLAAFKPEAYSGPEAAASGLAE 67

  Fly    57 -DRERSISKSPPLCCRDLGLYKLTQPKEIQPSARQPSNYLQYYAAAMDNNNHHHQATGTSNSSAA 120
             ..|...:.|||.|            ....|:|  |:.|...|.               ....|.
Mouse    68 LRAEMGPAPSPPKC------------SPAFPAA--PTFYPGAYG---------------DPDPAK 103

  Fly   121 DYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLSHDGSGLSRKKRSRAAFSHA 185
            |....|........|..||       .::.|.        :|.|.:.      |:::.|..||.|
Mouse   104 DPRADKKELCALQKAVELD-------KAETDG--------AERPRAR------RRRKPRVLFSQA 147

  Fly   186 QVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEAALLG----AS 246
            ||:||||||.||||||.|||.::|..|:||.|||||||||||||.|| |.|.....|||    .:
Mouse   148 QVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKR-QRQDQTLELLGPPPPPA 211

  Fly   247 KRVPVQVLVREDGSTTYAHMA--APGAGHGLDPALINIYRHQLQLAYGGLPLPQMQMPFPYF--- 306
            :|:.|.|||| ||.......|  ||..|.||:....|.|.:.   :|||....      |.:
Mouse   212 RRIAVPVLVR-DGKPCLGDPAAYAPAYGVGLNAYGYNAYPYP---SYGGAACS------PGYSCA 266

  Fly   307 -YPQHKVPQPIPPPTQSSSFVTASSASSSPVPIPIPGAVRPQRTPCPSPNGQMMSVESGAESVH 369
             ||  ..|....||        |:||:|:.|...: |.:...::| ..|.|     .||..::|
Mouse   267 AYP--AAPPAAQPP--------AASANSNFVNFGV-GDLNTVQSP-GMPQG-----NSGVSTLH 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeodomain	176..232	CDD:459649	38/55 (69%)
Nkx2-5	NP_032726.1	Homeodomain	144..194	CDD:459649	37/49 (76%)