Protein Alignment bap and Nkx2-5

DIOPT Version :10

• Sequence 1: NP_732637.1
• Gene: bap / 42537
• FlyBaseID: FBgn0004862
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_446103.2
• Gene: Nkx2-5 / 114109
• RGDID: 620520
• Length: 319
• Species: Rattus norvegicus
• Alignment Length: 388
• Identity: 117/388 - (30%)
• Similarity: 150/388 - (38%)
• Gaps: 112/388 - (28%)

  Fly    17 SKSLT-TPFSINDILTRSNPETRRMSSVD------------------SEPE----PEKLKPSSDR 58
            |.:|| ||||:.|||.... :.|.:::.|                  .:||    ||...|....
  Rat     4 SPALTHTPFSVKDILNLEQ-QQRSLAAGDLSARLEATLAPASCMLAAFKPEAYSGPEAAAPGLAE 67

  Fly    59 ---ERSISKSPPLCCRDLGLYKLTQPKEIQPSARQPSNYLQYYAAAMDNNNHHHQATGTSNSSAA 120
               |...:.|||.|            ....|:|  |:.|.:.|.               ....|.
  Rat    68 LRAELGPAPSPPKC------------SPAFPTA--PTFYPRAYG---------------DPDPAK 103

  Fly   121 DYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLSHDGSGLSRKKRSRAAFSHA 185
            |....|........|..||       .::.|.        :|.|.:.      |:::.|..||.|
  Rat   104 DPRADKKELCALQKAVELD-------KAETDG--------AERPRAR------RRRKPRVLFSQA 147

  Fly   186 QVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEAALLG----AS 246
            ||:||||||.||||||.|||.::|..|:||.|||||||||||||.|| |.|.....|||    .:
  Rat   148 QVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKR-QRQDQTLELLGPPPPPA 211

  Fly   247 KRVPVQVLVREDGSTTYAHMA--APGAGHGLDPALINIYRHQLQLAYGGL---PLPQMQMPFPYF 306
            :|:.|.|||| ||.......|  ||..|.||:....|.|.:.   .|||.   |.......:|..
  Rat   212 RRIAVPVLVR-DGKPCLGDSAAYAPAYGVGLNAYGYNAYPYP---GYGGAACSPAYSCAAAYPAA 272

  Fly   307 YPQHKVPQPIPPPTQSSSFVTASSASSSPVPIPIPGAVRPQRTPCPSPNGQMMSVESGAESVH 369
            .|   ..|| |....:|:||.......:.|..|            ..|.|     .||..::|
  Rat   273 PP---AAQP-PAAAANSNFVNFGVGDLNTVQSP------------GMPQG-----NSGVSTLH 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bap	NP_732637.1	Homeodomain	176..232	CDD:459649	38/55 (69%)
Nkx2-5	NP_446103.2	Homeodomain	144..194	CDD:459649	37/49 (76%)