Protein Alignment ETHR and PK2-R2

DIOPT Version :8

• Sequence 1: NP_001287439.1
• Gene: ETHR / 42523
• FlyBaseID: FBgn0038874
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Alignment Length: 509
• Identity: 136/510 (27%)
• Similarity: 219/510 (43%)
• Gaps: 93/510 (18%)

  Fly     3 PQIPSYIRTTAMFFCIVIMLLGVVGNVMVPIVIVKTKDMRNSTNIFLTNLSIADLLVLLVCTPTV 67
            |..|..:..|......:|.:.||:||::..|||.:...|..:||.:|.||:|:|:::|....|..
  Fly    59 PMTPLSLLATLSVGYALIFIAGVLGNLITCIVISRNNFMHTATNFYLFNLAISDMILLCSGMPQD 123

  Fly    68 LVEVNTRPETWVLGHEMCKAVPFVELTVAHASVLTILAISFERYYAICEPLKAGYVCTKGRAILI 132
            |..: ..|:.:.....:|.....:..|.|:|:||||.|.:.|||.|||.|.:...:....||:..
  Fly   124 LYNL-WHPDNYPFSDSICILESVLSETAANATVLTITAFTVERYIAICHPFRQHTMSKLSRAVKF 187

  Fly   133 CVLAWGIAALFTSPILWVAEYKLAEYIDGSSVAVCLTQAISDWTLAFFLMTISVFFVVPFVTLVV 197
            ....|..|.|...|  ...::.:.....|:|   |..:  :|:....|.::..:||..|...:.|
  Fly   188 IFAIWIAALLLALP--QAIQFSVVMQGMGTS---CTMK--NDFFAHVFAVSGFLFFGGPMTAICV 245

  Fly   198 LYGIIARNLVSNRAAMLRARPTK---PELSLKARKQVVLMLGAVVLSFFVCLLPFRVLTLWIILS 259
            ||.:|...|  .|:.:|:|.|.:   ....:.|:.:|:.||.||.::||:|..||....|..:..
  Fly   246 LYVLIGVKL--KRSRLLQALPRRCYDVNRGISAQTRVIRMLVAVAVAFFICWAPFHAQRLMAVYG 308

  Fly   260 TDQTLHDLGLVRYYSLL-YFCRIMLYLNSAMNPILYNLMSTKFRRGFKRLCQDAGRLLLELVTLG 323
            :...:........:|:| |...::.:|::.:||:|||:||.|||..||             |||.
  Fly   309 STSGIESQWFNDVFSILDYTSGVLYFLSTCINPLLYNIMSHKFREAFK-------------VTLA 360

  Fly   324 RR----KEDSSRG---------RRGTLSLGMGTNTNTNTNSSNATGATSSSILSRSSNRRCSEDI 375
            |.    .::..||         |..|.||.:.|..:..|..::.  ||:::.|:.|:|
  Fly   361 RHFGLGGKNQGRGLPHTYSALRRNQTGSLRLHTTDSVRTTMTSM--ATTTTGLNGSAN------- 416

  Fly   376 SRTRLKIEMQMPCGSDLEAMAMLQHSTLGKGI-ARRVS-DSRLMPLRNH-------QPRRH-KPQ 430
                         ||.       ..:|.|:.: ..||| ||..|..:|.       .|||. :.|
  Fly   417 -------------GSG-------NGTTTGQSVRLNRVSLDSVQMQGQNRSRQDLFDNPRRMLQTQ 461

  Fly   431 I----------SFDEESLEENKRSEAKIPTKCR-EKLP---GIAREIVNLTENT 470
            |          |..||.|:.......:.||.|. ::|.   .|:|..:.||..|
  Fly   462 ISQLSSVGDAHSLLEEDLQFPGEPLQRQPTMCSIDELTDDLAISRSRLKLTRIT 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ETHR	NP_001287439.1	7tm_4	18..>143	CDD:304433	41/125 (33%)
		7tm_1	27..294	CDD:278431	75/271 (28%)
		7tm_4	<102..307	CDD:304433	61/209 (29%)
PK2-R2	NP_731788.1	7tm_1	83..344	CDD:278431	75/271 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C68214600
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			P	PTHR24243
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R5416
	3	3.060