Protein Alignment meigo and SLC35A1

DIOPT Version :10

• Sequence 1: NP_650949.1
• Gene: meigo / 42510
• FlyBaseID: FBgn0250820
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_006407.1
• Gene: SLC35A1 / 10559
• HGNCID: 11021
• Length: 337
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 68/318 - (21%)
• Similarity: 120/318 - (37%)
• Gaps: 85/318 - (26%)

  Fly    51 YALALVWVQ-----------CLCNYVFAKVLLTIRPQKEDTTNAGSYVA---------------C 89
            |.:||.:.:           .:|.....|:||::....::|.:.|.:.|               .
Human    27 YTIALRYTRTSDKELYFSTTAVCITEVIKLLLSVGILAKETGSLGRFKASLRENVLGSPKELLKL 91

  Fly    90 SLTYLLAMVSTNMAMRWVPYPTAVVGKSAKPIPV---MILGVLIGRKSYSWTRYACVLTIVLGVI 151
            |:..|:..|..|||...:....|.|.:....:.:   .:..||:..::.|..::..|..:..||.
Human    92 SVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWVSVFMLCAGVT 156

  Fly   152 LFMYKEGKVSNLPAE-TTLLGEVLLFLSLSMDGLTGAVQERIRAASAPS----GQQMMRAMNFWS 211
            |..:|..:.:.:..| ..|||...:.:::...|..|...|::..:|..|    ..||     :.|
Human   157 LVQWKPAQATKVVVEQNPLLGFGAIAIAVLCSGFAGVYFEKVLKSSDTSLWVRNIQM-----YLS 216

  Fly   212 TLMLGVAMVFTGEAKE---------FMYFTIRHPEAWTHLSLIAVCGVLGQFFIFLMVASFGPLA 267
            .:::.:|.|:..:..|         :.|:      .|              |.|||  ||.|.|.
Human   217 GIIVTLAGVYLSDGAEIKEKGFFYGYTYY------VW--------------FVIFL--ASVGGLY 259

  Fly   268 CSVVT----TTRKFF--------TVLCSVLLFGNVLIARQWLGAVLVFAALFVDMLYG 313
            .|||.    ...|.|        :.:.||:|||..:.....||.:||..:::   |||
Human   260 TSVVVKYTDNIMKGFSAAAAIVLSTIASVMLFGLQITLTFALGTLLVCVSIY---LYG 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
meigo	NP_650949.1	UAA	8..311	CDD:462479	65/314 (21%)
SLC35A1	NP_006407.1	Nuc_sug_transp	8..314	CDD:398009	66/316 (21%)
		Disordered. /evidence=ECO:0000250|UniProtKB:Q61420	316..337