DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7009 and R74.7

DIOPT Version :9

Sequence 1:	NP_650947.1	Gene:	CG7009 / 42508	FlyBaseID:	FBgn0038861	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_497843.1	Gene:	R74.7 / 175543	WormBaseID:	WBGene00011281	Length:	337	Species:	Caenorhabditis elegans

Alignment Length:	299	Identity:	144/299 - (48%)
Similarity:	199/299 - (66%)	Gaps:	30/299 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGRTSKDKRDIFYRLAKEQGWRARSAFKLLQADETFQLLEGLTRAVDLCAAPGSWSQVLAKRLYE 65
            ||:||:|||||:||||||..|||||||||:|.|:.||:|:|:.||||||||||||||||:||||
Worm     1 MGKTSRDKRDIYYRLAKENKWRARSAFKLMQIDDEFQILKGVRRAVDLCAAPGSWSQVLSKRLY- 64

  Fly    66 PLPPEEREKVKIIAVDLQGMAPIEGVKQLRADISKESTAEAIIEFFGGEKAQIVVSDGAPDSTGM 130
                ||.::.||:|:|||.||||.||.||:.||:...||..:|:.|.|||:.||:.|||||.||:
Worm    65 ----EEDQEAKIVAIDLQPMAPIPGVIQLQGDITSVDTANQVIKHFSGEKSDIVICDGAPDVTGI 125

  Fly   131 HDFDSYVQGELLLSALSISTFILEEGGSFVSKIYRADRTSRLYTQLKRFFKNVCVFKPSASRNSS 195
            |..|.::|.||:|:|.:|::.:|:|||:|::||:|:..:|.||.|:|::||.|.:.||.:||.||
Worm   126 HSLDEFMQAELILAAFNITSHVLKEGGNFLAKIFRSRNSSLLYAQMKKYFKKVYLAKPRSSRQSS 190

  Fly   196 IEAFVVAREFCLPDGYKPCNLTTEWHDQPESWVGRKKESPPVVQVPFVAYKGEL---DSDRTYDL 257
            .||||:..::..|:|:.|....|.......|.:     ||.::. .||.. |:|   ||:::|.|
Worm   191 CEAFVLCLDYSPPEGFVPTMGKTSLDATDASAI-----SPDIID-GFVTC-GDLSGWDSEKSYPL 248

  Fly   258 --------GE-------NYVYKEPVQQPLTAAYQDILQK 281
                    ||       .|.:|:.||.|...||:..|.|
Worm   249 DIDACFPKGEIDEEQKKRYEFKDVVQPPTDPAYKAALDK 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7009	NP_650947.1	RlmE	4..205	CDD:223370	116/200 (58%)
R74.7	NP_497843.1	RlmE	3..204	CDD:223370	116/205 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161700
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0293
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54241
OrthoDB	1	1.010	-	-		D1362679at2759
OrthoFinder	1	1.000	-	-		FOG0004400
OrthoInspector	1	1.000	-	-		otm14685
orthoMCL	1	0.900	-	-		OOG6_102125
Panther	1	1.100	-	-	O	PTHR10920
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3115
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.760