Protein Alignment Bdbt and FKBPL

DIOPT Version :10

• Sequence 1: NP_650943.1
• Gene: Bdbt / 42503
• FlyBaseID: FBgn0038857
• Length: 286
• Species: Drosophila melanogaster
• Sequence 2: NP_071393.2
• Gene: FKBPL / 63943
• HGNCID: 13949
• Length: 349
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 62/291 - (21%)
• Similarity: 107/291 - (36%)
• Gaps: 53/291 - (18%)

  Fly     9 WEDKNRGLAKKVIGLQFTEMDKPTIISTVEFSVNKKATNLG-----GRPSKYLVSDESATYPQKH 68
            |...:....||:: ::...:|||.:.|..      :...||     |.|..:.
Human    97 WYCPDGSFVKKIV-IRGHGLDKPKLGSCC------RVLALGFPFGSGPPEGWT------------ 142

  Fly    69 SLEMGTSLTAVDCYLELL---LQQFVPGETAACSITTKTGERIEFELKLEKIVKNTQVEKLSAAE 130
            .|.||......:.:.||:   |:....||.|...:...:|..:  .|.|....:.....:|..:|
Human   143 ELTMGVGPWREETWGELIEKCLESMCQGEEAELQLPGHSGPPV--RLTLASFTQGRDSWELETSE 205

  Fly   131 IYEVALRLKESGVATFKT-FPKFAFDYFVRAAKLLITYKPFDKLTKKTNGINGQAVEELFIQIQT 194
            ...:|...:..|...|:. .|:.|...:.||.:||:|..|        .|...:.|      :..
Human   206 KEALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPP--------PGPPERTV------LHA 256

  Fly   195 NLAACLLQEKRYEHVIYHTQFVETEESPSEKSIYRRALAYYHLKEFAKAQATIERM-----PNYE 254
            |||||.|...:.:........|...|....|::|||.:|...|....||.|.::::     .|..
Human   257 NLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRA 321

  Fly   255 EKREFSKLRDNIAVSWKDSKAHYKEVVQRMF 285
            .:.|..|    :.:..|:..|...:.:::||
Human   322 AQEELGK----VVIQGKNQDAGLAQGLRKMF 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bdbt	NP_650943.1	FKBP_N_2	9..117	CDD:375495	23/115 (20%)
FKBPL	NP_071393.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..55
		TPR	200..>338	CDD:440225	36/155 (23%)
		TPR 1	210..243		9/32 (28%)
		TPR repeat	210..238	CDD:276809	7/27 (26%)
		TPR repeat	251..281	CDD:276809	8/35 (23%)
		TPR 2	252..285		9/38 (24%)
		TPR 3	286..319		9/32 (28%)
		TPR repeat	286..314	CDD:276809	9/27 (33%)