Protein Alignment HHEX and YHP1

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_010739.3
• Gene: YHP1 / 852062
• SGDID: S000002859
• Length: 353
• Species: Saccharomyces cerevisiae
• Alignment Length: 292
• Identity: 63/292 - (21%)
• Similarity: 105/292 - (35%)
• Gaps: 65/292 - (22%)

  Fly     2 DIATKSSKAAFSIENILEQKSSSHRSQSRRGSSQSPVAVTAGIA--------TPHALAMPKASLA 58
            :|.|.:|.:.|.:..:   .:::..|..:......|:|.:|.|.        :|.....||..
Yeast    13 NIITGTSNSPFQLHTL---PNTNFPSDDQGDIRLPPLAASAHIVRPVVNIYKSPCDEERPKRK-- 72

  Fly    59 TGSSSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVLQ 123
              |..|....|....|::..||:.        |.:.|.:...||....:...|..:...|::|
Yeast    73 --SPQAVDFLSQRVTTSMTPLSKP--------KKLSSHSPFTPTVRVCSKEQPPQSMHSYKKV-- 125

  Fly   124 LQKNPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPF---TMDCEGFP--NPASAAAALYCNAYPAA 183
                 ::..|     ..||.|.:.||...::...|   |...|.||  .|....|.|
Yeast   126 -----NILTP-----LSAAKAVLTPTTRKEKKRSFAFITHSQETFPKKEPKIDNARL-------- 172

  Fly   184 SFYMSNFGVKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAK 248
                    .:||  :.|.:|.:...|:..|......:..:|..|:.|..::::.|:.||||:|
Yeast   173 --------ARRK--RRRTSSYELGILQTAFDECPTPNKAKRIELSEQCNMSEKSVQIWFQNKR-- 225

  Fly   249 WRRANLSKRSASAQGPIAGAAVGSPSSASSSS 280
             :.|...|.|    |..:...|.|..|.|..|
Yeast   226 -QAAKKHKNS----GNTSHCKVHSNDSMSMIS 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	13/50 (26%)
YHP1	NP_010739.3	COG5576	123..278	CDD:227863	39/167 (23%)