Protein Alignment HHEX and Noto

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001178943.1
• Gene: Noto / 502857
• RGDID: 1562910
• Length: 245
• Species: Rattus norvegicus
• Alignment Length: 269
• Identity: 62/269 - (23%)
• Similarity: 103/269 - (38%)
• Gaps: 85/269 - (31%)

  Fly    64 AAPTPSP-SSATNIY-----------------DLSREAAAAQYAMKSM-------DSSAVLAP-- 101
            ::|.|.| ||.|.:.                 .|:|....:.::::::       :.||...|
  Rat     2 SSPVPQPASSGTQVQPGDLGPCPVAVSPVVPNHLARGRLESSFSVEAILARPETREHSATSLPLS 66

  Fly   102 --TSLRFNPIYPDPASLFYQQVLQLQKNPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCEG 164
              |||.|       .|:...|||....:...::|.:.:..:              |...:|.|
  Rat    67 TCTSLNF-------GSVSQYQVLPWVCSTGTWLPTYLSVGI--------------YPMCSMSC-- 108

  Fly   165 FPNPASAAAALYC--------NAYP--------AASFYMSNFGVKRKGGQIR--FTSQQTKNLEA 211
              .|......|:|        :..|        |.:..:.:...:|...::|  |:.||...||.
  Rat   109 --MPGLNVTHLFCQQGLRLTGSELPSCLGPLKRAPTVNLQDHNTERHQKRVRTMFSEQQLGELEK 171

  Fly   212 RFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRRAN---------LSKRSASAQGPI-- 265
            .||....|..:||..||.:|.||:.||:.||||||.|:::..         :.:.|.|::|.:
  Rat   172 VFAKQHNLVGKERAQLAARLHLTENQVRIWFQNRRVKYQKQQKLKSPPPDAMEEPSNSSEGNVRN 236

  Fly   266 --AGAAVGS 272
              |.|.|||
  Rat   237 EDAEAGVGS 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	25/52 (48%)
Noto	NP_001178943.1	Homeodomain	155..211	CDD:459649	25/55 (45%)