Protein Alignment HHEX and pitx3

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_991238.1
• Gene: pitx3 / 402974
• ZFINID: ZDB-GENE-041229-4
• Length: 293
• Species: Danio rerio
• Alignment Length: 141
• Identity: 41/141 - (29%)
• Similarity: 59/141 - (41%)
• Gaps: 45/141 - (31%)

  Fly   193 KRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRR------ 251
            |::..:..|||||.:.|||.|..::|.....|..:|:...||:.:|:.||:|||||||:
Zfish    59 KQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ 123

  Fly   252 ANLSKRSASAQ---------GPIAG---------AAVGSPSSASS-------------------- 278
            |.|.|....||         ...:|         :...||.||.|
Zfish   124 AELCKNGFGAQFNGLMQPYDDMYSGYSYNNWATKSLASSPLSAKSFPFFNSMNVSPLSSQPMFSP 188

  Fly   279 -SSVPVLNLGS 288
             ||:|.:|:.|
Zfish   189 PSSIPSMNMAS 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	23/50 (46%)
pitx3	NP_991238.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..69		2/9 (22%)
		Homeodomain	61..117	CDD:459649	23/55 (42%)
		OAR	251..268	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	255..268
		Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:O35160	260..264