Protein Alignment HHEX and HOXD9

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_055028.3
• Gene: HOXD9 / 3235
• HGNCID: 5140
• Length: 352
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 68/284 - (23%)
• Similarity: 94/284 - (33%)
• Gaps: 81/284 - (28%)

  Fly    34 SQSPVAVT-AGIATPHALAMPKASLAT----------------------------GSSSAAPTPS 69
            ||.|.|.. :|:..|:....|.|:.|:                            |.....|:|.
Human    84 SQPPAAAAMSGLYHPYVPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGGGPGRGPSPG 148

  Fly    70 PSSATN--IYDLSREA----AAAQYAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVLQLQKNP 128
            ||...|  .|.:..|.    |.|..|..:..||..|:.:|.|        ......:..|....|
Human   149 PSGPANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSSSKR--------TECSVARESQGSSGP 205

  Fly   129 SLFMPHF-QAAAVAAAAAVQP-------TAYCDQYSPFTMDCEGFPNPASAAAALYCNA------ 179
            ......| |..|.||.....|       |.......|..  |...|.|.       |:.
Human   206 EFSCNSFLQEKAAAATGGTGPGAGIGAATGTGGSSEPSA--CSDHPIPG-------CSLKEEEKQ 261

  Fly   180 ------------YPAASFYMSNFGVKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLK 232
                        .|||::..:....|::   ..:|..||..||..|..:.||:.:.|..:|..|.
Human   262 HSQPQQQQLDPNNPAANWIHARSTRKKR---CPYTKYQTLELEKEFLFNMYLTRDRRYEVARILN 323

  Fly   233 LTDRQVKTWFQNRRAKWRRANLSK 256
            ||:||||.||||||.|.::.:..|
Human   324 LTERQVKIWFQNRRMKMKKMSKEK 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	24/50 (48%)
HOXD9	NP_055028.3	Hox9_act	11..>164	CDD:461369	16/79 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..208		18/89 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	229..276		6/55 (11%)
		Homeodomain	286..337	CDD:459649	22/53 (42%)