Protein Alignment HHEX and HOXC11

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_055027.1
• Gene: HOXC11 / 3227
• HGNCID: 5123
• Length: 304
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 63/281 - (22%)
• Similarity: 102/281 - (36%)
• Gaps: 73/281 - (25%)

  Fly    33 SSQSPVAVTAGIATPHALAMPKA-SLATGSSSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSS 96
            ||..|.|.:..|:.|::..:|.. .::.|...:......:|.::.|      |||...|    ..
Human    48 SSFLPQAPSRQISYPYSAQVPPVREVSYGLEPSGKWHHRNSYSSCY------AAADELM----HR 102

  Fly    97 AVLAPTSL-------------RFNPIYP--DPASLFYQQVLQLQKNPSLFMPHFQAAAVAAAAAV 146
            ..|.|:::             ..:|..|  .||. ||..|.:....|..|...|.
Human   103 ECLPPSTVTEILMKNEGSYGGHHHPSAPHATPAG-FYSSVNKNSVLPQAFDRFFD---------- 156

  Fly   147 QPTAYCDQYSPFTM-------DCEGFP-------------------------NPASAAAALYCNA 179
              .|||....|...       :.:|.|                         ||:|:.:|.....
Human   157 --NAYCGGGDPPAEPPCSGKGEAKGEPEAPPASGLASRAEAGAEAEAEEENTNPSSSGSAHSVAK 219

  Fly   180 YPAASFYMSNFGVKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQN 244
            .||.....:....::|  :..::..|.:.||..|..:.|::.|:|..|:..|.|||||||.||||
Human   220 EPAKGAAPNAPRTRKK--RCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQN 282

  Fly   245 RRAKWRRANLSKRSASAQGPI 265
            ||.|.::.:..:....:..|:
Human   283 RRMKEKKLSRDRLQYFSGNPL 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	23/50 (46%)
HOXC11	NP_055027.1	DUF3528	42..161	CDD:432284	28/135 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..237		9/72 (13%)
		Homeodomain	233..289	CDD:459649	24/57 (42%)