Protein Alignment HHEX and Nkx3-1

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001029316.1
• Gene: Nkx3-1 / 305999
• RGDID: 1305369
• Length: 238
• Species: Rattus norvegicus
• Alignment Length: 258
• Identity: 70/258 - (27%)
• Similarity: 102/258 - (39%)
• Gaps: 60/258 - (23%)

  Fly    44 IATPHALAMPKASLATGSSS--AAPTPSPSSATN--IYDLSREAAAAQYAMKSMDSSAVLAPTSL 104
            :|.|.     :|.|..|..|  |||.......|:  |.|:.|:.|..:....|...
  Rat     4 VAEPQ-----EARLEAGGRSPWAAPPTQSKRLTSFLIQDILRDHAERRGGQPSTPQ--------- 54

  Fly   105 RFNPIYPDPASLFYQQVLQLQ------KNPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCE 163
              :...|||......::.:.:      ::|    |..:::.....|..:..|:.:.|   .:|||
  Rat    55 --HQCQPDPKRDSASELDEAEGSSVTLEDP----PGIRSSPTETRAETESDAHFETY---LLDCE 110

  Fly   164 GFPNPASAAAALYCNAYPAASFYMSNFGVKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLA 228
            ..|..:||...   ...|            :|..:..|:..|...||.:|:..||||..||.|||
  Rat   111 HTPVLSSAPQV---TKQP------------QKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLA 160

  Fly   229 LQLKLTDRQVKTWFQNRRAKWRRANLSKRSASAQGPIAGAAVGSPSSASSSSVPVLNLGSGSR 291
            ..||||:.|||.||||||.|.:|..||:            .:|.....|:.|:|.|...|.||
  Rat   161 KNLKLTETQVKIWFQNRRYKTKRRQLSE------------DLGVLEKNSTLSLPTLKDDSLSR 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	28/50 (56%)
Nkx3-1	NP_001029316.1	Homeodomain	127..183	CDD:459649	29/55 (53%)