Protein Alignment HHEX and Hoxd13

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001099356.1
• Gene: Hoxd13 / 288154
• RGDID: 1308417
• Length: 331
• Species: Rattus norvegicus
• Alignment Length: 298
• Identity: 77/298 - (25%)
• Similarity: 118/298 - (39%)
• Gaps: 80/298 - (26%)

  Fly     4 ATKSSKAAFSIENILEQKSSSHRSQSRRGSSQSPVAVTAGIATPHALAMPKASLATGSSSAAPTP 68
            |..::.||.:..:......:|.|:.|...||.|.|..|...| |.|...|  :.|..:::|||..
  Rat    48 AAAAAAAAAAAASSFAYPGTSERTGSSSSSSSSAVIATRPEA-PVAKECP--APAAAATAAAPPG 109

  Fly    69 SPSSATNIY--------DLSREAAAAQYAMKS--------------MDSSAVLAPTSLRFNPIYP 111
            :|:.....:        .:|......|.|:||              ||.|. ||.:|:..|.:
  Rat   110 APALGYGYHFGNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVEKYMDVSG-LASSSVPTNEV-- 171

  Fly   112 DPASL----FYQQVLQLQKNPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPF---------TMDCE 163
             ||..    |||.    ..:|...:|                .|.|..|.|         .:..|
  Rat   172 -PARAKEVSFYQG----YTSPYQHVP----------------GYIDMVSTFGSGEPRHEAYISME 215

  Fly   164 GFPNPASA---AAALYC-NAYPAAS-FYMSNFG-----------VKRKGGQIR--FTSQQTKNLE 210
            |:.:...|   .:.:|| ...|..| |:.|:|.           |.|:|.:.|  :|..|.|.||
  Rat   216 GYQSWTLANGWNSQVYCAKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYTKLQLKELE 280

  Fly   211 ARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAK 248
            ..:|.:|:::.::||.::....|::|||..||||||.|
  Rat   281 NEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVK 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	21/51 (41%)
Hoxd13	NP_001099356.1	HoxA13_N	<113..160	CDD:463521	7/46 (15%)
		Homeodomain	265..321	CDD:459649	21/54 (39%)