DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HHEX and ceh-51

DIOPT Version :9

Sequence 1:	NP_650938.2	Gene:	HHEX / 42495	FlyBaseID:	FBgn0038852	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_507685.1	Gene:	ceh-51 / 180233	WormBaseID:	WBGene00013583	Length:	234	Species:	Caenorhabditis elegans

Alignment Length:	201	Identity:	61/201 - (30%)
Similarity:	81/201 - (40%)	Gaps:	31/201 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 PSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSLRFNPIYP------------DPASLFYQQVL 122
            |.|::|:...|....|......:|.||   :|.|:..:|.||            ||..|:|||.|
Worm    16 PLSSSNLNSTSAITNATVMEYSTMPSS---SPGSMSSSPAYPAAYQAPSPCYVADPNQLYYQQQL 77

  Fly   123 QLQKNPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCEGFPNPASAAAALYCNAYPAASFYM 187
            ....|..|...|.||......|..|     .|||  .:....||:|..|..|.:..  |..||..
Worm    78 AHNGNDMLVQAHAQAYQAQCFAWFQ-----QQYS--QLSPSSFPHPMVAHHAGFIP--PPPSFLH 133

  Fly   188 SNF-------GVKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNR 245
            ...       ..||:|.:..|:..|...|..||.....:..:|||.|...:.|:..|:|.|||||
Worm   134 HQHQQHPRAPSEKRRGARTPFSDSQLYALRTRFEQCDTIKVDERRKLGAVIGLSPEQIKIWFQNR 198

  Fly   246 RAKWRR 251
            |.|.|:
Worm   199 RFKLRK 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeobox	200..250	CDD:278475	19/49 (39%)
ceh-51	NP_507685.1	Homeobox	151..204	CDD:365835	19/52 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910