Protein Alignment HHEX and Dlx3

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_034185.1
• Gene: Dlx3 / 13393
• MGIID: 94903
• Length: 287
• Species: Mus musculus
• Alignment Length: 158
• Identity: 49/158 - (31%)
• Similarity: 70/158 - (44%)
• Gaps: 14/158 - (8%)

  Fly   127 NPSLFMPHFQAAAVAAAAAVQPTA---YCDQYSPFTMDCEGFPNPASAAAALYCNAYPAASFYMS 188
            ||..:...|....:|...|..|.:   |...|..:....|   .|..|...:.....|.|...|.
Mouse    61 NPYTYHHQFNLNGLAGTGAYSPKSEYTYGGSYRQYGAYRE---QPLPAQDPVSVKEEPEAEVRMV 122

  Fly   189 NFGVKRKGGQIR--FTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRR 251
            | |..:|..:.|  ::|.|...|:.||..::||:..||..||.||.||..|||.||||||:|::
Mouse   123 N-GKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFK- 185

  Fly   252 ANLSKRSASAQGPIAGAAVGSPSSASSS 279
                |...:.:.|:..:...|.|.|.:|
Mouse   186 ----KLYKNGEVPLEHSPNNSDSMACNS 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	26/52 (50%)
Dlx3	NP_034185.1	DLL_N	27..107	CDD:463567	11/48 (23%)
		COG5576	<109..224	CDD:227863	38/107 (36%)
		Homeodomain	130..186	CDD:459649	26/60 (43%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:O60479	131..181		23/49 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		4/15 (27%)