Protein Alignment Calx and slc8a1b

DIOPT Version :10

• Sequence 1: NP_001247215.1
• Gene: Calx / 42481
• FlyBaseID: FBgn0013995
• Length: 973
• Species: Drosophila melanogaster
• Sequence 2: NP_001034233.1
• Gene: slc8a1b / 797199
• ZFINID: ZDB-GENE-060110-3
• Length: 944
• Species: Danio rerio
• Alignment Length: 916
• Identity: 442/916 - (48%)
• Similarity: 594/916 - (64%)
• Gaps: 83/916 - (9%)

  Fly   100 CSEGLVLPLWMPQRNISVGDRLVRGFVYFVLLIYLFVGVSIIADRFMAAIEAITSIERAVVVKGP 164
            |:.|::||:|.|. |.|.||::.|..||||.|:|:|:|||||||||||:||.|||.|:.:.:|.|
Zfish    59 CAPGVILPVWEPP-NPSFGDKVARATVYFVALVYMFLGVSIIADRFMASIEVITSQEKEITIKKP 122

  Fly   165 NNTKQVMHVRIWNETVANLTLMALGSSAPEILLSVIEIYAKDFESGDLGPGTIVGSAAYNLFMII 229
            |.......||||||||:||||||||||||||||||||:...:||:|||||.|||||||:|:|:||
Zfish   123 NGETTTTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFEAGDLGPSTIVGSAAFNMFVII 187

  Fly   230 AVCMIWIPAGEVRRIRHLRVFFVTALFSVFAYVWLWLILSVFTPGVILVWEAIVTLLFFPLTVLW 294
            .:|:..:|.||.|:::|||||||||.:|:|||:|::|||:|.:||::.|||.::||.|||:.|::
Zfish   188 GICVYVVPDGEHRKVKHLRVFFVTAAWSIFAYLWMYLILAVLSPGIVQVWEGLLTLFFFPICVVF 252

  Fly   295 AYIAERRLLVYKYMDKNYRVNK-RGTVVAGEHDQ-------VEMDAEKGPKQPMVTS-------- 343
            |:||:||||.|||:.|.||..| ||.::..|.|:       :|||.:      |:.|
Zfish   253 AWIADRRLLFYKYVYKRYRAGKHRGMIIETEGDRPLPSKVDIEMDGK------MLNSHAVDFLDG 311

  Fly   344 -----ARGNDAEAFDEARREYITLLTELRQKYPDADLEQLEMMAQEQVLARSSKSRAFYRIQATR 403
                 ....|.:. ||||||...:|.||:||:||.::|||..:|..|||::..|||||||.||||
Zfish   312 TLALELEDKDLDE-DEARREMAKILKELKQKHPDKEVEQLIELANYQVLSQQQKSRAFYRCQATR 375

  Fly   404 KMVGSGNLMRK---IQERAHSDLTEVKAQLHAGDDEEADDPI-RMYFEPGHYTVMENCGEFEVRV 464
            .|.|:||:::|   .|.|....:.||::      |...:||| :::|:|..|..:||||...|.|
Zfish   376 LMTGAGNILKKHAADQARKAVSMHEVRS------DTGENDPISKIFFDPCSYQCLENCGTVAVNV 434

  Fly   465 VRR-GDISTYASVEYETQDGTASAGTDFVGRKGLLSFPPGVDEQRFRIEVIDDDVFEEDECFYIR 528
            :|| ||::...|||:.|:||||:||:|:...:|.:.|.||..::..|:.:||||:|||||.|.|.
Zfish   435 IRRGGDLNQTVSVEFRTEDGTANAGSDYEFTEGTVVFKPGETQKEIRVGIIDDDIFEEDENFLIH 499

  Fly   529 LFN---PSEG--------------VKLAVPMIATVMILDDDHAGIFAFTDSVFEITESVGRFELK 576
            |.|   ..||              ..|.:|..|||.|.||||||||.|.:.|..::||||..|:|
Zfish   500 LSNVRVVHEGDEPETTEANHVETIATLGLPSTATVTIFDDDHAGIFTFEEPVTHVSESVGVMEVK 564

  Fly   577 VMRYSGARGTVIVPYWTENDTAT-ESKDYEGARGELVFENNESEKFIDLFILEESSYEKDVSFKV 640
            |:|.|||||.|.|||.|...||. ..:|:|.:.|.|.|:|:|..|.|.:.:|....|.|..||.:
Zfish   565 VLRTSGARGVVSVPYKTIEGTARGGGEDFEDSHGFLEFQNDEILKTITVRVLNREEYHKQCSFFI 629

  Fly   641 HIGEPRLAPDDTNKESFFNRFFEKHEHSGEPTHDELAAKIKEVEKKPVQDLTELDRILLLSKPRN 705
            .:..|           .:.|      .......||....:||.|:....:..|..||..:.||..
Zfish   630 ELQTP-----------LWRR------RGWTVYRDEEKEVVKEEEEPLTGEEEEERRIAEMGKPML 677

  Fly   706 GELTTAYVRIRESQEFKATVDKLVAKANVSAVLGTSSWKEQFKDALTVIPADESEFDNDDE---E 767
            |:.....|.|.||.|||.|||||:.|.|::.::||:||::||.:|:||...:    |:|||   |
Zfish   678 GDHPRVEVIIEESYEFKNTVDKLIKKTNLALLVGTNSWRDQFIEAITVSAGE----DDDDEECGE 738

  Fly   768 EEVPSCFSYVSHFVCLFWKVLFAFVPPTDICGGYVTFVVSIFVIGVITAIIGDAASYFGCALNIK 832
            |::||||.||.||:.:|||||||||||||...|:..|||||.:|||:||.|||.||:|||.:.:|
Zfish   739 EKLPSCFDYVMHFLTVFWKVLFAFVPPTDYWNGWACFVVSIIMIGVLTAFIGDLASHFGCTIGLK 803

  Fly   833 DSVTAILFVALGTSIPDTFASMIAAKHDEGADNCIGNVTGSNAVNVFLGIGLAWTIAAVYHSSHG 897
            |||||::|||||||:||||||.:||..|:.||..|||||||||||||||||:||:|||:||:|.|
Zfish   804 DSVTAVVFVALGTSVPDTFASKVAAIQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHNSKG 868

  Fly   898 MTFNVEPGTIGFAVALFCGEALIAIMLIMFRRWHKGIGAELGGPKVSKYISAAILVFLWVFYVVI 962
            ..|.||||.:.|:|.||...|.|.:.::|:|| ...||.|||||:.:|.::..:.|.||:.|::.
Zfish   869 NDFRVEPGNLAFSVTLFTIFAFICVAVLMYRR-RPDIGGELGGPRTAKALTTMLFVSLWLLYILF 932

  Fly   963 CILEAY 968
            ..||||
Zfish   933 SSLEAY 938

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Calx	NP_001247215.1	caca	4..973	CDD:273296	442/916 (48%)
slc8a1b	NP_001034233.1	caca	36..944	CDD:273296	442/916 (48%)