Protein Alignment Calx and slc8a1

DIOPT Version :10

• Sequence 1: NP_001247215.1
• Gene: Calx / 42481
• FlyBaseID: FBgn0013995
• Length: 973
• Species: Drosophila melanogaster
• Sequence 2: XP_012819269.1
• Gene: slc8a1 / 100492166
• XenbaseID: XB-GENE-984129
• Length: 978
• Species: Xenopus tropicalis
• Alignment Length: 940
• Identity: 437/940 - (46%)
• Similarity: 610/940 - (64%)
• Gaps: 90/940 - (9%)

  Fly   100 CSEGLVLPLWMPQRNISVGDRLVRGFVYFVLLIYLFVGVSIIADRFMAAIEAITSIERAVVVKGP 164
            |.||::||:|.|| |.|.||::.|..||||.::|:|:||||||||||::||.|||.|:.:.:|.|
 Frog    52 CKEGVILPIWEPQ-NPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKP 115

  Fly   165 NNTKQVMHVRIWNETVANLTLMALGSSAPEILLSVIEIYAKDFESGDLGPGTIVGSAAYNLFMII 229
            |.......||||||||:||||||||||||||||||||:...:|::|||||.|||||||:|:|:||
 Frog   116 NGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFQAGDLGPSTIVGSAAFNMFIII 180

  Fly   230 AVCMIWIPAGEVRRIRHLRVFFVTALFSVFAYVWLWLILSVFTPGVILVWEAIVTLLFFPLTVLW 294
            |:|:..:|.||:|:|:|||||||||.:|:|||.||::|||||:|||:.|||.::|..|||:.|::
 Frog   181 ALCVYVVPDGEIRKIKHLRVFFVTAAWSIFAYTWLYMILSVFSPGVVEVWEGLLTFFFFPICVVF 245

  Fly   295 AYIAERRLLVYKYMDKNYRVNK-RGTVVAGEHDQ------VEMDAEKGPKQPMVTSARGNDAEAF 352
            |::|:||||.|||:.|.||..| ||.::..|.|:      :|||.:          ...:..|.|
 Frog   246 AWVADRRLLFYKYVYKRYRAGKQRGMIIETEGDRPSSKADIEMDGK----------VLNSHTETF 300

  Fly   353 ----------------DEARREYITLLTELRQKYPDADLEQLEMMAQEQVLARSSKSRAFYRIQA 401
                            :||||:...:|.||:||:|:.::|||..:|..|||::..||||||||||
 Frog   301 LDGSLVLEVDEKDQDEEEARRDMAKILKELKQKHPEKEIEQLIELANYQVLSQQQKSRAFYRIQA 365

  Fly   402 TRKMVGSGNLMRKIQERAHSDLTEVKAQLH-AGDDEEADDPI-RMYFEPGHYTVMENCGEFEVRV 464
            ||.|.|:||:::    |..:|.......:| ...|...:||: ::|||...|..:||||...:.:
 Frog   366 TRLMTGAGNILK----RHAADQARKAVSMHEVNTDVVENDPVSKIYFEQATYQCLENCGTVALTI 426

  Fly   465 VRR-GDISTYASVEYETQDGTASAGTDFVGRKGLLSFPPGVDEQRFRIEVIDDDVFEEDECFYIR 528
            ||| ||::....|::.|:||:|:||:|:...:|.:.|.||..::..|:.:||||:|||||.|.:.
 Frog   427 VRRGGDLTNTVYVDFRTEDGSANAGSDYEFTEGTIIFKPGETQKELRVGIIDDDIFEEDENFLVH 491

  Fly   529 LFNPSEGVK----------------LAVPMIATVMILDDDHAGIFAFTDSVFEITESVGRFELKV 577
            |.|.....:                |.....|||.|.||||||||.|.::|..::||||..|:||
 Frog   492 LSNVRVNAENTEANLESNHVTPLACLGATCTATVTIFDDDHAGIFTFEETVTHVSESVGIMEVKV 556

  Fly   578 MRYSGARGTVIVPYWTENDTAT-ESKDYEGARGELVFENNESEKFIDLFILEESSYEKDVSFKVH 641
            :|.|||||||||||.|...||. ..:|:|...|:|.|:|:|..|.|.:.|:::..|||:.:|.:.
 Frog   557 LRTSGARGTVIVPYKTVEGTAKGGGEDFEDTCGQLEFQNDEIVKIISVKIIDDEEYEKNKTFFLE 621

  Fly   642 IGEPRLAPDDTNKESFFNRF------FEKHEHS-------GEPTHDELAAKIKEV---------- 683
            :|||||......|....|..      .:|.:.:       |:|...::..:...:
 Frog   622 VGEPRLVEMSEKKALLLNELDLKGAELQKRDFTITGKILYGKPVLRKVQVRDHPIPSTVIILTEE 686

  Fly   684 --EKKPVQDLTELD-RILLLSKPRNGELTTAYVRIRESQEFKATVDKLVAKANVSAVLGTSSWKE 745
              ||:|:....|.: ||..:.:|..||.|...:.|.||.|||:|||||:.|.|::.|:||:||:|
 Frog   687 NEEKQPLTSKEEEERRIAEMGRPVLGEHTRLEIIIEESYEFKSTVDKLIKKTNLALVVGTNSWRE 751

  Fly   746 QFKDALTVIPADESEFDNDDE--EEEVPSCFSYVSHFVCLFWKVLFAFVPPTDICGGYVTFVVSI 808
            ||.:|:||   ...|.|:|||  ||::||||.||.||:.:||||||||||||:...|:..|:|||
 Frog   752 QFIEAITV---SAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSI 813

  Fly   809 FVIGVITAIIGDAASYFGCALNIKDSVTAILFVALGTSIPDTFASMIAAKHDEGADNCIGNVTGS 873
            .:||::||.|||.||:|||.:.:||||||::|||||||:||||||.:||..|:.||..|||||||
 Frog   814 SMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGS 878

  Fly   874 NAVNVFLGIGLAWTIAAVYHSSHGMTFNVEPGTIGFAVALFCGEALIAIMLIMFRRWHKGIGAEL 938
            ||||||||||:||:|||:||:::|..|.|:|||:.|:|.||...|.|.:.::::|| ...||.||
 Frog   879 NAVNVFLGIGVAWSIAAIYHAANGDVFRVQPGTLAFSVTLFTIFAFINVGVLLYRR-RPEIGGEL 942

  Fly   939 GGPKVSKYISAAILVFLWVFYVVICILEAY 968
            |||:.:|.::.|:...||:.|:....||||
 Frog   943 GGPRTAKLLTTALFTLLWLLYIFFSSLEAY 972

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Calx	NP_001247215.1	caca	4..973	CDD:273296	437/940 (46%)
slc8a1	XP_012819269.1	caca	1..978	CDD:273296	437/940 (46%)