Protein Alignment Oct-TyrR and htr1d

DIOPT Version :9

• Sequence 1: NP_524419.2
• Gene: Oct-TyrR / 42452
• FlyBaseID: FBgn0004514
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001139158.1
• Gene: htr1d / 556429
• ZFINID: ZDB-GENE-090409-3
• Length: 386
• Species: Danio rerio
• Alignment Length: 506
• Identity: 150/506 - (29%)
• Similarity: 235/506 - (46%)
• Gaps: 155/506 - (30%)

  Fly    95 ASILGLQLAVPEWEALLTALVLSVIIVLTIIGNILVILSVFTYKPLRIVQNFFIVSLAVADLTVA 159
            |::|.||:::        :.:|:::.:.|.:.|..||.::|..:.|....||.|.|||..||.|:
Zfish    28 ATLLSLQISI--------SAMLAIVTLATALSNAFVIATIFLTRKLHTPANFLIGSLAATDLLVS 84

  Fly   160 LLVLPFNVAYSILGRWEFGIHLCKLWLTCDVLCCTSSILNLCAIALDRYWAITDPINYAQKRTVG 224
            :||:|.::.|::...|..|..:|.:||:.|:..||:|||:||.|||||||||||.:.|:::||:.
Zfish    85 ILVMPISIVYTVSKTWTLGQIVCDIWLSSDITFCTASILHLCVIALDRYWAITDALEYSKRRTMR 149

  Fly   225 RVLLLISGVWLLSLLISSPPLIGWNDWPDEFTSATPCEL-TSQRGYVIYSSLGSFFIPLAIMTIV 288
            |..|:|..||::|:.||.|||. |.. .......|.|.: |.|..|.:||:.|:|::|..::.|:
Zfish   150 RAALMIVIVWVISVSISLPPLF-WRQ-AKAHEELTECMVNTDQISYTLYSTFGAFYVPTVLLMIL 212

  Fly   289 YIEIFVATRRRL-RERARANKLNTIALKSTELEPMANSSPVAASNSGSKSRLLASWLCCGRDRAQ 352
            |..|:||.|.|: :..|.:.|      :.|..:.:.||:              .|.||
Zfish   213 YGRIYVAARSRIFKTPATSGK------RFTAAQLIQNSA--------------GSSLC------- 250

  Fly   353 FATPMIQNDQESISSETHQPQDSSKAGPHGNSDPQQQHVVVLVKKSRRAKTKDSIKHGKTRGGRK 417
                       |::|.::|
Zfish   251 -----------SLNSTSNQ---------------------------------------------- 258

  Fly   418 SQSSSTCEPHGEQQLLPAGGDGGSCQPGGGHSGGGKSDAEISTESGSDPKGCIQVCVTQADEQTS 482
                   |.|     |.|||.|||   |||..|||.|  .:.|.|         |.|..||.
Zfish   259 -------EGH-----LNAGGGGGS---GGGGGGGGGS--PLFTNS---------VKVKLADS--- 294

  Fly   483 LKLTPPQSSTGVAAVSVTPLQKKTSGVNQFIEEKQKISLSKERRAARTLGIIMGVFVICWLPFFL 547
                                          :.|::::..::|::|.:|||||:|.|::||||||:
Zfish   295 ------------------------------VLERKRLCAAREKKATKTLGIILGAFIVCWLPFFV 329

  Fly   548 MYVILPFCQTCCPTNKFKNFITWLGYINSGLNPVIYTIFNLDYRRAFKRLL 598
            ..:::..|:.|.......:..|||||:||.:||||||.||.|:::||.:|:
Zfish   330 FTLVMGVCKDCWYHPVLFDVFTWLGYLNSLINPVIYTAFNDDFKQAFHKLI 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oct-TyrR	NP_524419.2	7tmA_tyramine_octopamine_R-like	110..>294	CDD:320188	72/184 (39%)
		TM helix 1	111..137	CDD:320188	6/25 (24%)
		TM helix 2	144..170	CDD:320188	12/25 (48%)
		TM helix 3	182..212	CDD:320188	19/29 (66%)
		TM helix 4	224..247	CDD:320188	11/22 (50%)
		TM helix 5	266..294	CDD:320188	10/27 (37%)
		7tm_GPCRs	<519..594	CDD:475119	33/74 (45%)
		TM helix 6	528..550	CDD:410628	13/21 (62%)
		TM helix 7	562..587	CDD:410628	13/24 (54%)
htr1d	NP_001139158.1	7tmA_5-HT1B_1D	31..376	CDD:320455	146/497 (29%)
		TM helix 1	36..62	CDD:320455	6/33 (18%)
		TM helix 2	69..95	CDD:320455	12/25 (48%)
		TM helix 3	107..137	CDD:320455	19/29 (66%)
		TM helix 4	149..172	CDD:320455	11/23 (48%)
		TM helix 5	190..219	CDD:320455	10/28 (36%)
		TM helix 6	304..334	CDD:320455	15/29 (52%)
		TM helix 7	344..369	CDD:320455	13/24 (54%)