Protein Alignment Septin2 and SEPTIN7

DIOPT Version :10

• Sequence 1: NP_524417.1
• Gene: Septin2 / 42438
• FlyBaseID: FBgn0014029
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: XP_011513958.1
• Gene: SEPTIN7 / 989
• HGNCID: 1717
• Length: 460
• Species: Homo sapiens
• Alignment Length: 410
• Identity: 164/410 - (40%)
• Similarity: 248/410 - (60%)
• Gaps: 45/410 - (10%)

  Fly    22 GHVGFDSLPDQLVNKSVQNGFVFNVMCIGETGLGKSTLMDTLFNTSFEST----PSPHTLPSVKL 82
            |:|||.:||:|:..|||:.||.|.:|.:||:|||||||:::||.|...|.    ||.....:|::
Human    29 GYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEYPGPSHRIKKTVQV 93

  Fly    83 KAHTYELQESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFENYLQEELKIKRSLVTCHDS 147
            :.....::|..|:|.|||.||.|:||.::..:.::.|:||||::||:||..|.::.|..:.  |:
Human    94 EQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMP--DN 156

  Fly   148 RIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVELQRFKAKIIQELNANGVH 212
            |:..|||||.|:|||||.||:..||:|..||||||:||||||::..|.|:||.:|::|:..:.:.
Human   157 RVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIK 221

  Fly   213 IYQFP-TDDETVAETNTSMNSHIPFAVVGSTEFIKVGNKLIRARQYPWGTVQVENETHCDFVKLR 276
            ||:|| ||||...:....:...:|.|||||...|:|..|.:|.||||||..:|||..||||..||
Human   222 IYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILR 286

  Fly   277 EMLIRTNMEDMREKTHTRHYELYRQKRLEQMGFSDVDS------------------DNKPISFQQ 323
            .|||||:|:|:::.|:..|||.||.::|..:.::.||:                  |..|::
Human   287 NMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKHLMITLNIRDRSPLA--- 348

  Fly   324 TFEAKRSNHLAELQSKEEEVRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAEEKRKLEESRK 388
            ..|.:|..|:|:::..|.|:.|:|..:||||..:||:||              ||.:|....|.|
Human   349 QMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSE--------------AEVQRTFLASEK 399

  Fly   389 ALEED---YLDFQRRKQQLA 405
            .|::.   .:|.|..|:.::
Human   400 GLQKKRHRVMDSQSHKKVIS 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Septin2	NP_524417.1	CDC_Septin	40..308	CDD:206649	125/272 (46%)
		PTZ00121	<285..393	CDD:173412	34/125 (27%)
SEPTIN7	XP_011513958.1	CDC_Septin	47..317	CDD:206649	125/271 (46%)